338983-45-2Relevant academic research and scientific papers
Facile and rapid synthesis of some novel polysubstituted imidazoles by employing magnetic Fe3O4 nanoparticles as a high efficient catalyst
Karami, Bahador,Eskandari, Khalil,Ghasemi, Abdolmohammad
, p. 601 - 613 (2012)
Multicomponent, one-pot, highly efficient, and environmentally adapted synthesis of some novel polysubstituted imidazoles by the use of various aldehydes, benzil, aliphatic, and aromatic primary amines and ammonium acetate in the presence of Fe3O4 nanoparticles as catalyst under solvent-free condition is explained. A highly efficient role of Fe3O4 nanoparticles as catalyst in this synthesis was shown. By this advantage, several polysubstituted imidazoles as pharmaceutical important molecules can be prepared in high yield and high purity. This method is very easy and rapid for the synthesis of imidazole derivatives. All products were deduced from their IR and NMR spectroscopic data. The Fe3O4 nanoparticles were characterized by powdered X-ray diffraction (XRD), transmission electron microscopy (TEM), and FT-IR spectroscopy. TUeBITAK.
New conditions for the effective synthesis of tri and tetrasubstituted imidazoles catalysed by recyclable indium (III) triflate and magnesium sulfate heptahydrate
Karami, Bahador,Ferdosian, Roghayeh,Eskandari, Khalil
, p. 41 - 45 (2014/02/14)
A one-pot three or four component reaction of wide range of aromatic aldehydes, benzil, aliphatic and aromatic primary amines and ammonium acetate is reported for the synthesis of tri/tetra-substituted imidazoles under solvent-free conditions. Indium (III) trifluoromethanesulfonate and magnesium sulfate heptahydrate as two highly efficient and recyclable catalysts perform a key factor to synthesis of imidazole derivatives with high yields.
Tungstate sulfuric acid (TSA): A green and highly efficient catalyst for novel and known polysubstituted imidazoles synthesis
Karami, Bahador,Eskandari, Khalil,Azizi, Mahboobeh
, p. 722 - 732 (2014/03/21)
Tungstate sulfuric acid (TSA) was composed of anhydrous sodium tungstate and chlorosulfonic acid with a new modified and efficient method. Catalyst was characterized by powdered X-ray diffraction (XRD), X-ray fluorescence (XRF), FT-IR spectroscopy and titration with NaOH (0.1 N). In the present study, highly efficient role of TSA as a catalyst in polysubstituted imidazoles synthesis as pharmaceuticaly important molecules via condensation between a wide range of aryl aldehydes, primary amines, benzil, and ammonium acetate in solventless conditions is reported. Therefore, new application of this catalyst to synthesize some novel imidazoles is introduced.
MCM-41-SO3H as a highly efficient sulfonic acid nanoreactor for the rapid and green synthesis of some novel highly substituted imidazoles under solvent-free condition
Mahdavinia, Gholam Hossein,Amani, Ali Mohammad,Sepehrian, Hamid
experimental part, p. 703 - 708 (2012/05/05)
Nanosized MCM-41-SO3H based on ordered mesoporous silica material with a covalent sulfonic acid group was synthesized and used as acid catalyst for the new, simple, convenient and green synthesis of 2,4,5-trisubstituted and 1,2,4,5-tetra-substituted imidazoles. Also some of synthesis products are new. Echo-friendly protocol, short reaction times, easy and quick isolation of the products and excellent yields are the main advantages of this procedure.
An effective and new method for the synthesis of polysubstituted imidazoles by the use of CrCl3.6H2O as a green and reusable catalyst: Synthasis of some novel imidazole derivatives
Karami, Bahador,Eskandari, Khalil,Farahi, Mahnaz,Barmas, Akram
experimental part, p. 473 - 479 (2012/07/14)
New, efficient and environmentally adapted synthesis of polysubstituted imidazoles in one-pot is found. The multicomponent reaction of various aldehydes, benzil, aliphatic and aromatic primary amines and ammonium acetate under solvent-free condition is explained. The highly efficient role of CrCl3.6H2O as catalyst in this synthesis was shown. By this advantage, several polysubstituted imidazoles as pharmaceutical important molecules can be prepared in high yield and high purity. This method is a very easy and a rapid reaction for the synthesis of imidazole derivatives. The crude products recrystallized to afford the crystalline pure products. Furthermore, catalyst exhibited remarkable reusable activity.
Facile and rapid synthesis of polysubstituted imidazoles by employing Y(NO3)3×6H2O as catalyst
Karami, Bahador,Dehghani, Fatemeh Mohammadpour,Eskandari, Khalil
, p. 147 - 153,7 (2020/09/09)
An efficient and environmentally adapted synthesis of polysubstituted imidazoles in one-pot and multicomponent reaction of various aldehydes, benzil, aliphatic and aromatic primary amines and ammonium acetate under solvent-free condition is reported. Highly efficient role of Y(NO3) 3×6H2O as catalyst in this synthesis was shown. By this advantage, several polysubstituted imidazoles as pharmaceutical important molecules can be prepared in high yield and high purity. This method is very easy and rapid for the synthesis of imidazole derivatives. All products were deduced from their IR and NMR spectroscopic and elemental analysis data. The catalyst exhibited remarkable reusable activity.
Synthesis of 2,4,5-trisubstituted imidazoles catalyzed by [Hmim]HSO 4 as a powerful Broensted acidic ionic liquid
Khosropour, Ahmad R.
, p. 264 - 269 (2008/09/19)
An efficient and green procedure for the synthesis of 2,4,5-trisubstituted imidazoles with various aldehydes using a catalytic amount of 1-methylimidazolium hydrogenesulfate as an active and low cost Broensted acidic room temperature ionic liquid has been developed. The ionic liquid was easily separated from the reaction mixture and was recycled five times without any loss in activity.
