339018-66-5 Usage
Uses
Used in Pharmaceutical Industry:
(E)-3-(DIMETHYLAMINO)-1-[4-(2-PYRIMIDINYLOXY)PHENYL]-2-PROPEN-1-ONE is used as an inhibitor for enzymes CYP17 and CYP11B2, which are involved in steroid biosynthesis. Its application is primarily for the treatment of conditions such as cancer and Cushing's syndrome due to its ability to interfere with the steroid biosynthesis process.
Used in Neurological Research:
In the field of neurological research, (E)-3-(DIMETHYLAMINO)-1-[4-(2-PYRIMIDINYLOXY)PHENYL]-2-PROPEN-1-ONE is used as a potential candidate for the development of treatments for neurological disorders. (E)-3-(DIMETHYLAMINO)-1-[4-(2-PYRIMIDINYLOXY)PHENYL]-2-PROPEN-1-ONE has shown antidepressant and anxiolytic effects in animal studies, indicating its potential in addressing mental health conditions.
Used in Organic Synthesis:
Within the chemical industry, (E)-3-(DIMETHYLAMINO)-1-[4-(2-PYRIMIDINYLOXY)PHENYL]-2-PROPEN-1-ONE is utilized in organic synthesis processes. Its unique structure and properties make it a valuable component in the creation of various chemical compounds and substances.
Check Digit Verification of cas no
The CAS Registry Mumber 339018-66-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,3,9,0,1 and 8 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 339018-66:
(8*3)+(7*3)+(6*9)+(5*0)+(4*1)+(3*8)+(2*6)+(1*6)=145
145 % 10 = 5
So 339018-66-5 is a valid CAS Registry Number.
339018-66-5Relevant academic research and scientific papers
Synthesis and structure-activity relationship of aminopyrimidine IKK2 inhibitors
Bingham, Alistair H.,Davenport, Richard J.,Fosbeary, Richard,Gowers, Lewis,Knight, Roland L.,Lowe, Christopher,Owen, David A.,Parry, David M.,Pitt, Will R.
scheme or table, p. 3622 - 3627 (2009/04/06)
The synthesis and structure-activity relationship of a novel series of aminopyrimidines are exemplified. Results of key compounds from within this series in the E-selectin reporter cell assay are also reported.
