339201-10-4

Basic information

• Product Name: (R)-N-benzyloxycarbonyl-N-phthalimidoalanine methyl ester
• Synonyms: (R)-N-benzyloxycarbonyl-N-phthalimidoalanine methyl ester
• CAS NO: 339201-10-4
• Molecular Weight: 382.373
• Mol File: 339201-10-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (R)-N-benzyloxycarbonyl-N-phthalimidoalanine methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-N-benzyloxycarbonyl-N-phthalimidoalanine methyl ester(339201-10-4)
• EPA Substance Registry System: (R)-N-benzyloxycarbonyl-N-phthalimidoalanine methyl ester(339201-10-4)

Safety Data

• Hazardous Substances Data: 339201-10-4(Hazardous Substances Data)

Upstream product

• 27871-49-4 (S)-Methyl lactate 
• 287728-91-0 N-benzyloxycarbonylaminophthalimide 

Downstream Products

• 929720-04-7 C₂₉H₃₅N₃O₈ 
• 929720-09-2 C₁₇H₂₄N₂O₆ 
• 929720-24-1 2-(N-benzyloxycarbonyl-hydrazino)-propionic acid methyl ester 
• 929719-98-2 2-{N-benzyloxycarbonyl-N'-[2-(pyrrolidine-1-carbonyl)-benzoyl]-hydrazino}-propionic acid methyl ester 

Relevant articles and documents

Synthesis of Nα-Z, Nβ-Fmoc or Boc protected α-hydrazinoacids and study of the coupling reaction in solution of Nα-Z-α-hydrazinoesters

The preparation of chiral orthogonally protected Nα-Z, Nβ-Fmoc- or Boc-α-hydrazinoacids derivatives, directly suitable for SPPS, is described in six steps with good yields starting from the corresponding α-aminoacids. The coupling reaction assays performed in liquid phase between Nα-Z-hydrazinoesters and N-Fmoc-α-aminoacids demonstrated the low reactivity of the hydrazinoester derivatives. However, we found that the acid fluoride method allowed the formation of hydrazinodipeptides almost quantitatively.