339218-70-1

Basic information

• Product Name: 2-amino-4-(4-bromophenyl)-4H-pyrano[3,2-h]quinoline-3-carbonitrile
• Synonyms: 2-amino-4-(4-bromophenyl)-4H-pyrano[3,2-h]quinoline-3-carbonitrile
• CAS NO: 339218-70-1
• Molecular Weight: 378.228
• Mol File: 339218-70-1.mol

Chemical Properties

• CAS DataBase Reference: 2-amino-4-(4-bromophenyl)-4H-pyrano[3,2-h]quinoline-3-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-amino-4-(4-bromophenyl)-4H-pyrano[3,2-h]quinoline-3-carbonitrile(339218-70-1)
• EPA Substance Registry System: 2-amino-4-(4-bromophenyl)-4H-pyrano[3,2-h]quinoline-3-carbonitrile(339218-70-1)

Safety Data

• Hazardous Substances Data: 339218-70-1(Hazardous Substances Data)

Upstream product

• 148-24-3 8-quinolinol 
• 2826-24-6 4-bromobenzylidenemalononitrile 
• 1122-91-4 4-bromo-benzaldehyde 
• 109-77-3 malononitrile 

Relevant articles and documents

Cell cycle arrest and induction of apoptosis of newly synthesized pyranoquinoline derivatives under microwave irradiation

A set of 2-amino-4-aryl-4H-pyrano[3,2-h]quinoline-3-carbonitrile derivatives were prepared via a one-pot, three-component condensation reaction between the substituted hydroxyquinoline derivatives, some aryl and/or hetaryl aldehydes, and malononitrile in

Halogenated 2-amino-4H-pyrano[3,2-h]quinoline-3-carbonitriles as antitumor agents and structure–activity relationships of the 4-, 6-, and 9-positions

A series of halogenated 2-amino-4-aryl-4H-pyrano[3,2-h]quinoline-3-carbonitrile derivatives were prepared via interaction of 8-hydroxyquinoline, 5-chloro-8-hydroxyquinoline, and 8-hydroxy-2-methylquinoline with various α-cyanocinnamonitriles. The assignme

Ce-Zr/SiO2: A versatile reusable heterogeneous catalyst for three-component synthesis and solvent free oxidation of benzyl alcohol

Ce-Zr loaded on SiO2 as catalyst provides an extremely efficient method to synthesize pyranoquinolines. This catalyst is found to be superb for the three-component synthesis of target compounds and for the solvent-free liquid-phase oxidation of benzyl alcohols. The catalyst is fully recoverable and reusable with no loss of catalytic activity even after multiple cycles.

Synthesis, antitumor activity, and structure-activity relationship of some 4H-pyrano[3,2-h]quinoline and 7H-pyrimido[4′,5′:6,5]pyrano[3,2-h] quinoline derivatives

Several 4H-pyrano[3,2-h]quinoline (3a-d, 4a, 7a,b, 9a-c, 10a,b, 11a,b, and 13a-c) and 7H-pyrimido[4′,5′:6,5]pyrano[3,2-h]quinoline derivatives (8a-c) were obtained by treatment of 8-hydroxyquinoline (1a) and 8-hydroxy-2-methylquinoline (1b) with α-cyano-p

Synthesis of certain novel 4H-pyrano[3,2-h]quinoline derivatives

Treatment of 8-hydroxyquinoline 1a and 8-hydroxy-2-methylquinoline 1b with α-cyano-pchloro/bromocinnamonitriles 2a,b provided 4H-pyrano[3,2-h] quinoline-3-carbonitrile derivatives 3a-d, while treatment of (E) 2-(4-chlorostyryl)-8-hydroxyquinoline 7 with α