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[6, 7Bis(carboxymethoxy)coumarin4yl]methylguanosine3', 5'cyclic monophosphate (BCMCM-caged cGMP) is a chemical compound derived from guanosine-3',5'-cyclic monophosphate (cGMP) and 6,7-Bis(carboxymethoxy)coumarin-4-ylmethyl. It is a caged form of cGMP, which means that its photolysis can release free cGMP in a controlled manner when exposed to light. This unique property makes BCMCM-caged cGMP a valuable tool for studying cellular signaling pathways and biological processes that involve cGMP, as it allows for precise spatiotemporal control of cGMP release in live cells and tissues.

339291-52-0

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339291-52-0 Usage

Uses

Used in Neuroscience:
BCMCM-caged cGMP is used as a research tool for studying the role of cGMP in various neuronal processes. The controlled release of cGMP upon photolysis enables researchers to investigate the effects of cGMP on synaptic plasticity, neurotransmission, and other neuronal functions.
Used in Cardiovascular Research:
In the field of cardiovascular research, BCMCM-caged cGMP is employed as a tool to understand the role of cGMP in regulating vascular tone, blood pressure, and heart function. The ability to control cGMP release allows researchers to study its effects on smooth muscle relaxation, platelet aggregation, and other cardiovascular processes.
Used in Drug Development:
BCMCM-caged cGMP is used as a starting point for the development of novel therapeutics targeting cGMP signaling pathways. By understanding the precise mechanisms through which cGMP exerts its effects, researchers can design drugs that modulate cGMP levels or activity, potentially leading to new treatments for diseases related to cGMP signaling, such as erectile dysfunction, pulmonary hypertension, and certain types of cancer.
Used in Photopharmacology:
In the emerging field of photopharmacology, BCMCM-caged cGMP is utilized as a light-activated drug. By using light to control the release of cGMP, researchers can study the effects of cGMP on cellular processes in a highly controlled manner, allowing for the development of targeted therapies with minimal off-target effects.
Used in Cell Signaling Research:
BCMCM-caged cGMP is employed as a research tool for investigating the role of cGMP in various cell signaling pathways. The controlled release of cGMP upon photolysis enables researchers to study its effects on cellular processes such as cell proliferation, differentiation, and apoptosis, providing valuable insights into the regulation of these pathways and potential targets for therapeutic intervention.

Check Digit Verification of cas no

The CAS Registry Mumber 339291-52-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,3,9,2,9 and 1 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 339291-52:
(8*3)+(7*3)+(6*9)+(5*2)+(4*9)+(3*1)+(2*5)+(1*2)=160
160 % 10 = 0
So 339291-52-0 is a valid CAS Registry Number.

339291-52-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name cyclic guanosine-3',5'-monophosphate [6,7-bis(carboxymethoxy)coumarin-4-yl]methyl ester

1.2 Other means of identification

Product number -
Other names [6,7-bis(carboxymethoxy)coumarin-4-yl]methyl ester of cGMP

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:339291-52-0 SDS

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