3393-71-3Relevant academic research and scientific papers
Novel Sulfonaminoquinoline Hepcidin Antagonists
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Page/Page column 127, (2012/09/05)
The present invention relates to novel hepcidin antagonists, pharmaceutical compositions comprising them and the use thereof as medicaments for the use in the treatment of iron metabolism disorders, such as, in particular, iron deficiency diseases and anemias, in particular anemias in connection with chronic inflammatory diseases.
Synthesis of mono-and dialkylsubstituted 1,10-Phenanthrolines
Belser, Peter,Bernhard, Stefan,Guerig, Urs
, p. 2937 - 2944 (2007/10/03)
Starting from o-anisidine, alkylated 8-hydroxyquinolines 2 and 8-aminoquinolines 3 were obtained. From the latter, dialkylsubstituted 1,10-phenanthrolines 5 have been prepared in good yields. Reaction of unsubstituted 8-aminoquinoline under the same conditions, yielded monoalkylated 1,10-phenanthrolines 4.
