339316-63-1

Basic information

• Product Name: (R)-3-Dodecanoyloxy-tetradecanoic acid 2-oxo-2-phenyl-ethyl ester
• Synonyms: (R)-3-Dodecanoyloxy-tetradecanoic acid 2-oxo-2-phenyl-ethyl ester
• CAS NO: 339316-63-1
• Molecular Weight: 544.816
• Mol File: 339316-63-1.mol

Chemical Properties

• CAS DataBase Reference: (R)-3-Dodecanoyloxy-tetradecanoic acid 2-oxo-2-phenyl-ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-3-Dodecanoyloxy-tetradecanoic acid 2-oxo-2-phenyl-ethyl ester(339316-63-1)
• EPA Substance Registry System: (R)-3-Dodecanoyloxy-tetradecanoic acid 2-oxo-2-phenyl-ethyl ester(339316-63-1)

Safety Data

• Hazardous Substances Data: 339316-63-1(Hazardous Substances Data)

Upstream product

• 87357-65-1 (3R)-3-hydroxytetradecanoic acid phenacyl ester 
• 112-16-3 dodecanoyl chloride 
• 28715-21-1 (R)-3-hydroxytetradecanoic acid 
• 151763-75-6 (R)-3-hydroxytetradecanoic acid ethyl ester 
• 112-16-3 n-dodecanoyl chloride 

Downstream Products

• 91681-56-0 (3R)-3-dodecanoyloxytetradecanoic acid 
• 106022-61-1 benzyl 2-deoxy-2-<(3R)-3-dodecanoyloxytetradecanamido>-4,6-O-isopropylidene-β-D-glucopyranoside 
• 112166-34-4 Hexadecanoic acid (R)-1-{[(3R,4R,5S,6R)-5-(diphenoxy-phosphoryloxy)-2-hydroxy-6-hydroxymethyl-4-((R)-3-hydroxy-tetradecanoyloxy)-tetrahydro-pyran-3-ylcarbamoyl]-methyl}-dodecyl ester 
• 112166-33-3 (R)-3-Hydroxy-tetradecanoic acid (2R,3S,4R,5R)-3-(diphenoxy-phosphoryloxy)-5-((R)-3-dodecanoyloxy-tetradecanoylamino)-6-hydroxy-2-hydroxymethyl-tetrahydro-pyran-4-yl ester 
• 112166-31-1 Tetradecanoic acid (2R,3S,4R,5R)-3-(diphenoxy-phosphoryloxy)-5-((R)-3-dodecanoyloxy-tetradecanoylamino)-6-hydroxy-2-hydroxymethyl-tetrahydro-pyran-4-yl ester 
• 112166-30-0 benzyl 3-O-<(3R)-3-(benzyloxymethoxy)tetradecanoyl>-2-deoxy-4-O-(diphenylphosphono)-2-<(3R)-3-hexadecanoyloxytetradecanamido>-β-D-glucopyranoside 
• 112166-39-9 benzyl 2-deoxy-4-O-(diphenylphosphono)-2-<(3R)-3-dodecanoyloxytetradecanamido>-3-O-tetradecanoyl-6-O-trityl-β-D-glucopyranoside 
• 112166-27-5 benzyl 3-O-<(3R)-3-(benzyloxymethoxy)tetradecanoyl>-2-deoxy-4-O-(diphenylphosphono)-2-<(3R)-3-dodecanoyloxytetradecanamido>-β-D-glucopyranoside 
• 112166-29-7 Hexadecanoic acid (R)-1-{[(2R,3R,4R,5S,6R)-2-benzyloxy-4-((R)-3-benzyloxymethoxy-tetradecanoyloxy)-5-hydroxy-6-trityloxymethyl-tetrahydro-pyran-3-ylcarbamoyl]-methyl}-dodecyl ester 
• 112166-26-4 (R)-3-Benzyloxymethoxy-tetradecanoic acid (2R,3R,4R,5S,6R)-2-benzyloxy-3-((R)-3-dodecanoyloxy-tetradecanoylamino)-5-hydroxy-6-trityloxymethyl-tetrahydro-pyran-4-yl ester 
• 112174-35-3 benzyl 2-deoxy-4-O-(diphenylphosphono)-2-<(3R)-3-dodecanoyloxytetradecanamido>-3-O-tetradecanoyl-β-D-glucopyranoside 
• 112166-22-0 Tetradecanoic acid (2R,3R,4R,5S,6R)-2-benzyloxy-3-((R)-3-dodecanoyloxy-tetradecanoylamino)-5-hydroxy-6-trityloxymethyl-tetrahydro-pyran-4-yl ester 
• 112166-19-5 benzyl 3-O-<(3R)-3-(benzyloxymethoxy)tetradecanoyl>-2-deoxy-2-<(3R)-3-dodecanoyloxytetradecanamido>-4,6-O-isopropylidene-β-D-glucopyranoside 
• 112199-87-8 (R)-3-Benzyloxymethoxy-tetradecanoic acid (2R,3R,4R,5S,6R)-2-benzyloxy-3-((R)-3-dodecanoyloxy-tetradecanoylamino)-5-hydroxy-6-hydroxymethyl-tetrahydro-pyran-4-yl ester 

Relevant articles and documents

SYNTHETIC DERIVATIVES OF MPL AND USES THEREOF

In one aspect, the present disclosure provides compounds of formulae (I) and (II). In another aspect, a compound of formula (I) or (II) is formulated into compositions with an antigen, optionally with a vesicle. In some embodiments, compositions are administered intramuscularly.

SYNTHESIS OF NONREDUCING-SUGAR SUBUNIT ANALOGS OF BACTERIAL LIPID A CARRYING AN AMIDE-BOUND (3R)-3-ACYLOXYTETRADECANOYL GROUP

Two types of optically active, 4-O-phosphono-D-glucosamine derivatives related to the nonreducing-sugar subunit of bacterial lipid A, one being 2--2-deoxy-4-O-phosphono-3-O-tetradecanoyl-D-glucose (GLA-27 type; Gla-57 and GL