339538-63-5

Basic information

• Product Name: 7-[2-(5-trifluoromethyl-pyridin-2-yl)-benzoylamino]-quinoline-3-carboxylic acid
• Synonyms: 7-[2-(5-trifluoromethyl-pyridin-2-yl)-benzoylamino]-quinoline-3-carboxylic acid
• CAS NO: 339538-63-5
• Molecular Weight: 437.378
• Mol File: 339538-63-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 7-[2-(5-trifluoromethyl-pyridin-2-yl)-benzoylamino]-quinoline-3-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 7-[2-(5-trifluoromethyl-pyridin-2-yl)-benzoylamino]-quinoline-3-carboxylic acid(339538-63-5)
• EPA Substance Registry System: 7-[2-(5-trifluoromethyl-pyridin-2-yl)-benzoylamino]-quinoline-3-carboxylic acid(339538-63-5)

Safety Data

• Hazardous Substances Data: 339538-63-5(Hazardous Substances Data)

Upstream product

• 339538-62-4 7-[2-(5-Trifluoromethyl-pyridin-2-yl)-benzoylamino]-quinoline-3-carboxylic acid ethyl ester 

Downstream Products

• 339537-82-5 [R]-7-[2-(5-trifluoromethyl-pyridin-2-yl)-benzoylamino]-quinoline-3-carboxylic acid (1-pyridin-2-yl-ethyl)-amide 
• 339537-83-6 [S]-7-[2-(5-trifluoromethyl-pyridin-2-yl)-benzoylamino]-quinoline-3-carboxylic acid (phenyl-pyridin-2-yl-methyl)-amide 

Relevant articles and documents

7[4′-trifluoromethyl-biphenyl-2-carbonyl)amino]-quinoline-3-carboxylic acid amides, and method of inhibiting the secretion of apolipoprotein B

This invention relates to compounds of Formula I that inhibit the secretion of apolipoprotein B, to pharmaceutical compositions comprising the compounds, and to methods of treating and/or preventing atherosclerosis, obesity, diabetes, hyperlipidemia, hyperliproproteinemia, hypercholesterolemia, hypertriglyceridemia, hypoalphalipoproteinemia, pancreatitis, myocardial infarction, stroke, restenosis, or Syndrome X. This invention also relates to methods of reducing the secretion of apolipoprotein B and/or inhibiting microsomal triglyceride transfer protein.