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Usage

Uses

Used in Pharmaceutical Industry:
N-Acetyl-L-citrulline is used as an active pharmaceutical ingredient for the treatment of inflammatory bowel diseases. It is particularly effective in anti-integrin biologic therapy, which targets specific cell adhesion molecules involved in the inflammatory process. This therapy helps to reduce inflammation and alleviate symptoms associated with inflammatory bowel diseases.
Used in Sports Nutrition Industry:
N-Acetyl-L-citrulline is used as a sports supplement to enhance athletic performance and support muscle recovery. It promotes increased blood flow and nutrient delivery to muscles, which can lead to improved exercise capacity, reduced fatigue, and faster recovery times.
Used in Cosmetic Industry:
N-Acetyl-L-citrulline is used as an ingredient in cosmetic products for its skin health benefits. It has been shown to improve skin hydration, elasticity, and overall appearance. Additionally, it may have potential as an anti-aging ingredient due to its ability to support collagen production and protect against oxidative stress.
Used in Food and Beverage Industry:
N-Acetyl-L-citrulline is used as a functional ingredient in food and beverage products to support cardiovascular health and overall well-being. It has been found to improve endothelial function and support healthy blood vessel dilation, which can contribute to better blood flow and circulation. This can be particularly beneficial for individuals with certain cardiovascular conditions or those looking to maintain optimal heart health.

InChI:InChI=1/C8H15N3O4/c1-5(12)11-6(7(13)14)3-2-4-10-8(9)15/h6H,2-4H2,1H3,(H,11,12)(H,13,14)(H3,9,10,15)

Relevant academic research and scientific papers

Cosmetic composition

A composition suitable for topical application to mammalian skin and hair for inducing, maintaining or increasing hair growth comprises a hair growth promoter chosen from glutamine derivatives and salts thereof. The composition preferably also comprises an activity enhancer which may be chosen from hair growth stimulants, penetration enhancers and cationic polymers.

Cosmetic composition containing DOPA derivatives

A composition for topical application to human hair or skin contains a chemical analogue of dihydroxyphenyl alanine (DOPA). This chemical analogue can be absorbed by skin or by a hair follicle and metabolised in-vivo, thus leading to the formation of melanin in skin or to the growth of melanin-pigmented hair. Consequently the composition can give controlled skin darkening to mimic sun-induced tanning or can bring about the growth of dar hair in place of the grey or white hair.

Cosmestic composition

A composition suitable for topical application to mammalian skin and hair for inducing, maintaining or increasing hair growth comprises a hair growth promoter chosen from glutamic acid derivatives and salts thereof. The composition preferably also comprises an activity enhancer which may be chosen from hair growth stimulants, penetration enhancers and cationic polymers.

Hair growth composition containing citric acid esters

Triesters of citric acid are used for inducing, maintaining or increasing hair growth. Compositions for topical application to mammalian hair or scalp comprise an effective amount of from 1% to 99% by weight of an ester of citric acid having the structure (1): where, R1, R2 and R3 each independently represent a branched or unbranched alkyl, alkenyl, aryl, alkylaryl or arylalkyl group, each said group having from 1 to 18 carbon atoms, R4 represents -H, or a branched or unbranched saturated or unsaturated acyl, alkyl, aryl, alkylaryl or aylalkyl group having from 1 to 18 carbon atoms, in the presence of a cosmetically acceptable vehicle for the citric acid ester and in the absence of solid absorbent for the ester;, said effective amount of said ester being sufficient to increase hair growth in the rat, when said composition is applied topically thereto over a period of no more than three months, by at least 10% more than that obtainable using a control composition from which the said ester has been omitted, in accordance with the Rat Hair Growth Test.