33968-46-6Relevant articles and documents
Formal synthesis of tetrahydrolipstatin and tetrahydroesterastin
Tripathi, Divya,Kumar, Pradeep
experimental part, p. 884 - 890 (2012/09/21)
A versatile and efficient approach to (3S,5R)-methyl 3-(benzyloxy)-5- (methoxymethoxy)hexadecanoate, a key chiral building block and a common polyol fragment of the anti-tumor and anti-obesity agents tetrahydrolipstatin 3 and tetrahydroesterastin 4 using both hydrolytic kinetic resolution (HKR) and proline catalyzed sequential α-aminoxylation, followed by HWE-olefination reaction is described.