33977-11-6

Basic information

• Product Name: 5-Chloro-2-methoxy-benzoic acid hydrazide
• Synonyms: 5-Chloro-2-methoxy-benzoic acid hydrazide;5-chloro-2-methoxybenzohydrazide(SALTDATA: FREE);5-chloro-2-methoxybenzohydrazide
• CAS NO: 33977-11-6
• Molecular Formula: C₈H₉ClN₂O₂
• Molecular Weight: 200.6223
• Mol File: 33977-11-6.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Density: 1.312 g/cm³
• Refractive Index: 1.572
• PKA: 11?+-.0.10(Predicted)
• CAS DataBase Reference: 5-Chloro-2-methoxy-benzoic acid hydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Chloro-2-methoxy-benzoic acid hydrazide(33977-11-6)
• EPA Substance Registry System: 5-Chloro-2-methoxy-benzoic acid hydrazide(33977-11-6)

Safety Data

• Hazardous Substances Data: 33977-11-6(Hazardous Substances Data)

Usage

General Description

5-Chloro-2-methoxy-benzoic acid hydrazide, also known as 5-Chloro-2-methoxy-1H-benzo[d]imidazole-7-ol, is a chemical compound that is used in the pharmaceutical industry as a building block for the synthesis of various heterocyclic compounds with potential biological activity. It is also used as a reagent in organic synthesis to introduce the 5-Chloro-2-methoxy-benzoic acid hydrazide moiety into target molecules. 5-Chloro-2-methoxy-benzoic acid hydrazide has been studied for its potential anti-inflammatory, anti-cancer, and antimicrobial properties, making it a valuable tool for drug discovery and development. 5-Chloro-2-methoxy-benzoic acid hydrazide is important in the field of medicinal chemistry and is the subject of ongoing research for its potential therapeutic applications.

InChI:InChI=1/C8H9ClN2O2/c1-13-7-3-2-5(9)4-6(7)8(12)11-10/h2-4H,10H2,1H3,(H,11,12)

Upstream product

• 3438-16-2 5-chloro-2-methoxybenzoic acid 
• 68216-06-8 ethyl 5-chloro-2-methoxybenzoate 
• 33924-48-0 methyl 5-chloro-2-methoxybenzoate 

Downstream Products

• 133344-91-9 5-Chloro-2-methoxy-benzoic acid N'-(2-cyano-ethyl)-hydrazide 
• 133344-95-3 5-Chloro-2-methoxy-benzoic acid N',N'-bis-(2-cyano-ethyl)-hydrazide 
• 901449-59-0 N-(2-methoxy-5-chlorobenzamido)-N'-phenylthiourea 
• 1287116-19-1 4-(2-(5-chloro-2-methoxyphenyl)carbohydrazide)benzoic acid methyl ester 
• 1424272-37-6 4-(5-(5-chloro-2-hydroxyphenyl)-1,3,4-oxadiazol-2-yl)benzoic acid methyl ester 
• 1424272-39-8 methyl 4-(5-(5-chloro-2-methoxyphenyl)-1,3,4-oxadiazol-2-yl)benzoate 
• 133345-09-2 3-[5-(5-Chloro-2-methoxy-phenyl)-2-thioxo-[1,3,4]oxadiazol-3-yl]-propionitrile 
• 128772-81-6 5-(5-Chloro-2-methoxy-phenyl)-3H-[1,3,4]oxadiazol-2-one 

Relevant articles and documents

Complex, its preparation method, fluorinion sensor and method for detecting fluorinion

The invention provides a complex as shown in a chemical formula 1 in the specification, a preparation method of the complex, a fluorine ion sensor and a method for detecting a fluorine ion. In the chemical formula 1, m is an integer from 0 to 5, n is an integer from 0 to 4, R1, R2 and R3 are independently selected from a group composed of deuterium, tritium, halogen, a cyano group, an amino group, nitryl, hydroxyl, carboxyl, substituted or unsubstituted C2-C30 ether groups, substituted or unsubstituted C2-C30 ester groups, substituted or unsubstituted C1-C30 alkyls, substituted or unsubstituted C2-C30 alkenyls, substituted or unsubstituted C2-C30 alkynyls, substituted or unsubstituted C3-C30 cycloalkyls, substituted or unsubstituted C1-C30 alkoxyl groups, substituted or unsubstituted C3-C30 cycloalkoxyls, substituted or unsubstituted C5-C30 aryls, substituted or unsubstituted C5-C30 aryloxys and substituted or unsubstituted C3-C30 heteroaryls.

CRYOPYRIN INHIBITORS FOR PREVENTING AND TREATING INFLAMMATION

Inhibitors that are anti-inflammatory agents are provided, as are methods of using the analogs to inhibit inflammation and prevent or treat diseases and conditions associated with inflammation, such as heart failure and autoimmune diseases.