33987-02-9

Basic information

• Product Name: Benzo[g]quinazoline, 4-chloro-
• Synonyms: 4-Chlorbenzoquinazolin;
• CAS NO: 33987-02-9
• Molecular Formula: C12H7ClN2
• Molecular Weight: 214.654
• Mol File: 33987-02-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Benzo[g]quinazoline, 4-chloro-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzo[g]quinazoline, 4-chloro-(33987-02-9)
• EPA Substance Registry System: Benzo[g]quinazoline, 4-chloro-(33987-02-9)

Safety Data

• Hazardous Substances Data: 33987-02-9(Hazardous Substances Data)

Upstream product

• 33987-00-7 benzoquinazolin-4(3H)-one 
• 5959-52-4 2-Amino-3-naphthoic acid 
• 33987-00-7 benzo[g]quinazolin-4-ol 

Downstream Products

• 1373121-88-0 N-(4-chlorophenyl)benzo[g]quinazolin-4-amine 

Relevant articles and documents

Design, synthesis, and biological evaluation of conformationally constrained analogues of naphthol AS-E as inhibitors of CREB-mediated gene transcription

Cyclic AMP response element binding protein (CREB) is often dysregulated in cancer cells and is an attractive cancer drug target. Previously, we described naphthol AS-E (1) as a small molecule inhibitor of CREB-mediated gene transcription. To understand its bioactive conformation, a series of conformationally constrained analogues of 1 were designed and synthesized. Biological evaluation of these analogues suggests that the global energy minimum of 1 is the likely bioactive conformation.

Preparation of tricyclic compounds capable of inhibiting tyrosine kinases of the epidermal growth factor receptor family.

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