340041-92-1 Usage
Uses
Used in Pharmaceutical Research:
(S)-4-(4-NITRO-BENZYL)-OXAZOLIDIN-2-ONE is used as a research compound for its potential antimicrobial and antifungal properties. (S)-4-(4-NITRO-BENZYL)-OXAZOLIDIN-2-ONE's unique structure, including the nitrobenzyl group and (S)-configuration, may contribute to its effectiveness against various pathogens, making it a valuable target for the development of new drugs to combat resistant infections.
Used in Organic Synthesis:
In the field of organic synthesis, (S)-4-(4-NITRO-BENZYL)-OXAZOLIDIN-2-ONE serves as a key intermediate or building block for the synthesis of more complex molecules. Its reactivity, particularly due to the nitro group, allows for a range of chemical reactions that can be harnessed to create novel compounds with diverse applications, such as pharmaceuticals, agrochemicals, or materials science.
Used in Drug Design and Development:
(S)-4-(4-NITRO-BENZYL)-OXAZOLIDIN-2-ONE's potential biological activity, stemming from its oxazolidinone core and nitrobenzyl group, makes (S)-4-(4-NITRO-BENZYL)-OXAZOLIDIN-2-ONE a candidate for drug design and development. Researchers can explore its interactions with various biological targets, such as enzymes or receptors, to develop new therapeutic agents with improved efficacy and selectivity.
Used in Antimicrobial Resistance Research:
As antimicrobial resistance continues to be a global health concern, (S)-4-(4-NITRO-BENZYL)-OXAZOLIDIN-2-ONE may be employed in research aimed at understanding and overcoming resistance mechanisms. Its antimicrobial properties could be leveraged to develop new strategies to combat resistant bacteria, contributing to the development of more effective treatments for infectious diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 340041-92-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,4,0,0,4 and 1 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 340041-92:
(8*3)+(7*4)+(6*0)+(5*0)+(4*4)+(3*1)+(2*9)+(1*2)=91
91 % 10 = 1
So 340041-92-1 is a valid CAS Registry Number.
340041-92-1Relevant academic research and scientific papers
Rational design and generation of a bimodal bifunctional ligand for antibody-targeted radiation cancer therapy
Chong, Hyun-Soon,Ma, Xiang,Le, Thien,Kwamena, Baidoo,Milenic, Diane E.,Brady, Erik D.,Song, Hyun A.,Brechbiel, Martin W.
, p. 118 - 125 (2008/09/18)
An antibody-targeted radiation therapy (radioimmunotherapy, RIT) employs a bifunctional ligand that can effectively hold a cytotoxic metal with clinically acceptable complexation kinetics and stability while being attached to a tumor-specific antibody. Clinical exploration of the therapeutic potential of RIT has been challenged by the absence of adequate ligand, a critical component for enhancing the efficacy of the cancer therapy. To address this deficiency, the bifunctional ligand C-NETA in a unique structural class possessing both a macrocyclic cavity and a flexible acyclic moiety was designed. The practical, reproducible, and readily scalable synthetic route to C-NETA was developed, and its potential as the chelator of 212Bi, 213Bi, and 177Lu for RIT was evaluated in vitro and in vivo. C-NETA rapidly binds both Lu(III) and Bi(III), and the respective metal complexes remain extremely stable in serum for 14 days. 177Lu-C-NETA and 205/6Bi-C-NETA possess an excellent or acceptable in vivo biodistribution profile.
