34013-89-3Relevant academic research and scientific papers
Cs2CO3-Catalyzed Aerobic Oxidative Cross-Dehydrogenative Coupling of Thiols with Phosphonates and Arenes
Song, Song,Zhang, Yiqun,Yeerlan, Adeli,Zhu, Bencong,Liu, Jianzhong,Jiao, Ning
supporting information, p. 2487 - 2491 (2017/02/23)
An efficient Cs2CO3-catalyzed oxidative coupling of thiols with phosphonates and arenes that uses molecular oxygen as the oxidant is described. These reactions provide not only a novel alkali metal salt catalyzed aerobic oxidation, but also an efficient approach to thiophosphates and sulfenylarenes, which are ubiquitously found in pharmaceuticals and pesticides. The reaction proceeds under simple and mild reaction conditions, tolerates a wide range of functional groups, and is applicable to the late-stage synthesis and modification of bioactive molecules.
A thiophosphate synthetic method of compound and the method in a plurality of pharmaceutical application in the synthesis of (by machine translation)
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Paragraph 0139; 0140; 0141; 0142, (2017/07/20)
The invention discloses a having the general formula (III) of the thiophosphate synthetic method of compound, the purpose is to provide a novel, condition is simple, easy to industrial production of the thiophosphate synthetic method of compound. The method is to have the general formula (I) of the organophosphorus oxygen apperception compound having the general formula (II) with a mercaptan or phenyl-sulfhydryl apperception compound mixed, under the effects of catalyst, obtained by the reaction of the formula (III) of the thiophosphate compound. The method of the invention, can be cheap efficient synthesis of thiophosphate compounds, in actual production will have extensive application prospect. (by machine translation)
2-Chloro-2,4-dioxo-3-methyl-1,3,2-thiazaphospholidine. Comments on its phosphorylating properties
Modro, Agnes M.,Modro, Tomasz A.
, p. 2552 - 2554 (2007/10/02)
2-Alkoxy-2,4-dioxo-3-methyl-1,3,2-thiazaphospholidines undergo facile ring-opening reactions with chloride ion, and, in particular, with water.This reactivity may limit their value as first intermediates in the sequential synthesis of phosphoric diesters from the parent 2-chloro-2,4-dioxo-3-methyl-1,3,2-thiazaphospholidine.
The Preparation and the Use of 2-Chloro-2,4-dioxo-3-methyl-1,3,2-thiazaphospholidine, a Highly Reactive Reagent for the Synthesis of S-(N-Methylcarbamoylmethyl) Dialkyl Thiophosphates and Dialkyl Sodium Phosphates
Richter, Wolfgang,Ugi, Ivar
, p. 661 - 663 (2007/10/02)
The synthesis of 2-chloro-2,4-dioxo-3-methyl-1,3,2-thiazaphospholidine (4), a versatile and highly reactive reagent for the synthesis of unsymmetrical S-(N-methylcarbamoylmethyl) dialkyl thiophosphates and dialkyl sodium phosphates, and several reactions with alcohols are reported.
