340291-00-1Relevant academic research and scientific papers
Synthesis of aucubovir II, a new carbocyclic nucleoside analog
Bianco, Armandodoriano,Celletti, Lucia,Mazzei, Raffaele Antonio,Umani, Floriana
, p. 1331 - 1334 (2001)
The synthesis of a new carbocyclic nucleoside starting from aucubin, a natural methylcyclopentanoid monoterpene, has been performed, allowing the preparation of aucubovir II, a carbocyclic nucleoside analog with a highly functionalized cyclopentane ring. The stereocontrol of the coupling reaction was complete, utilizing the procedure described by Vorbrueggen with a purinic base.
