34045-35-7

Basic information

• Product Name: Phosphonochloridic acid, (2-chloroethyl)-, 2-chloroethyl ester
• CAS NO: 34045-35-7
• Molecular Formula: C4H8Cl3O2P
• Molecular Weight: 225.439
• Mol File: 34045-35-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Phosphonochloridic acid, (2-chloroethyl)-, 2-chloroethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphonochloridic acid, (2-chloroethyl)-, 2-chloroethyl ester(34045-35-7)
• EPA Substance Registry System: Phosphonochloridic acid, (2-chloroethyl)-, 2-chloroethyl ester(34045-35-7)

Safety Data

• Hazardous Substances Data: 34045-35-7(Hazardous Substances Data)

Upstream product

• 6294-34-4 bis(2-chloroethyl) 2-chloroethylphosphonate 
• 10026-13-8 phosphorus pentachloride 

Downstream Products

• 61293-54-7 (2-chloro-ethyl)-phosphonic acid anilide-(2-chloro-ethyl ester) 
• 690-12-0 (2-chloroethyl)phosphonic dichloride 

Relevant articles and documents

ORGANIC PHOSPHORUS COMPOUNDS 90. A CONVENIENT, ONE-STEP SYNTHESIS OF ALKYL- AND ARYLPHOSPHONYL DICHLORIDES

N,N-Disubstituted formamides such as dimethylformamide, N-formylpyrrolidine, N-formylpiperidine etc. and also pyridine and hexamethylphosphonic acid triamide catalyze the chlorination of phosphonates with thionyl chloride to give phosphonyl dichlorides in high yield.Thus RP(O)Cl2, R=CH3, C2H5, n-C12H25, C6H5, have been isolated in better than 90 per cent yield.The procedure is less satisfactory for the production of 2-chloroethylphosphonyl dichloride.Only a 34 per cent yield was realized.The chlorination proceeds very likely through the intermediate formation of the halfesters, RP(O)(OR)Cl since these could be isolated under favorable circumstances.