34046-73-6

Usage

Type of compound

Synthetic stimulant and thermogenic

Uses

Performance-enhancing drug, fat-burning and energy-boosting supplement, pre-workout supplement, weight-loss product

Adverse health effects

Increased heart rate, blood pressure, risk of heart attacks and strokes

Legal status

Banned by various sports organizations and regulatory bodies, considered illegal in many jurisdictions.

InChI:InChI=1/C10H13NO2.ClH/c1-10(2,11-13)9(12)8-6-4-3-5-7-8;/h3-7,11,13H,1-2H3;1H

Upstream product

• 10409-54-8 2-bromo-2-methyl-1-phenyl-propan-1-one 
• 5291-08-7 N-(2-methyl-1-oximino-1-phenyl-2-propyl)hydroxylamine 

Downstream Products

• 155126-45-7 N-(2-methyl-3-oxo-3-phenylpropyl-2)-C-(α-pyrrolyl)nitrone 
• 132402-19-8 2,2,5,5-Tetramethyl-3,6-diphenyl-2,5-dihydro-pyrazine 1,4-dioxide 
• 107259-85-8 Semicarbazone of 2-hydroxyamino-2-methyl-1-phenyl-1-propanone 
• 107259-86-9 Thiosemicarbazone of 2-Hydroxyamino-2-methyl-1-phenyl-1-propanone 
• 132417-72-2 C₁₆H₁₈N₄O₃ 
• 155126-43-5 4,4-dimethyl-5-phenyl-2-(α-pyrrolyl)-4H-imidazole-3-oxide 
• 107259-89-2 Semicarbazone of 2-acetoxyamino-2-methyl-1-phenyl-1-propanone 
• 107259-90-5 Thiosemicarbazone of 2-acetoxyamino-2-methyl-1-phenyl-1-propanone 

Relevant academic research and scientific papers

5-Aryl-2-(3,5-dialkyl-4-hydroxyphenyl)-4,4-dimethyl- 4H-imidazole 3-oxides and their redox species: How antioxidant activity of 1-hydroxy-2,5-dihydro- 1h-imidazoles correlates with the stability of hybrid phenoxyl-nitroxides

Cyclic nitrones of the imidazole series, containing a sterically hindered phenol group, are promising objects for studying antioxidant activity; on the other hand, they can form persistent hybrid phenoxyl-nitroxyl radicals (HPNs) upon oxidation. Here, a series of 5-aryl-4,4-dimethyl- 4H-imidazole 3-oxides was obtained by condensation of aromatic 2-hydroxylaminoketones with 4-formyl-2,6-dialkylphenols followed by oxidation of the initially formed N-hydroxy derivatives. It was shown that the antioxidant activity of both 1-hydroxy-2,5-dihydroimidazoles and 4H-imidazole 3-oxides increases with a decrease in steric volume of the alkyl substituent in the phenol group, while the stability of the corresponding HPNs generated from 4H-imidazole 3-oxides reveals the opposite tendency.