340728-59-8Relevant academic research and scientific papers
In vitro antifungal activity of new series of homoallylamines and related compounds with inhibitory properties of the synthesis of fungal cell wall polymers
Vargas M., Leonor Y.,Castelli, Maria V.,Kouznetsov, Vladimir V.,Urbina G., Juan M.,Lopez, Silvia N.,Sortino, Maximiliano,Enriz, Ricardo D.,Ribas, Juan C.,Zacchino, Susana
, p. 1531 - 1550 (2007/10/03)
The synthesis, in vitro antifungal evaluation and SAR studies of 101 compounds of the 4-aryl-, 4-alkyl-, 4-pyridyl or -quinolinyl-4-N-arylamino-1-butenes series and related compounds, are reported here. Active structures showed to inhibit (1,3)-β-D-glucan and mainly chitin synthases, enzymes that catalyze the synthesis of the major fungal cell wall polymers.
Transformations of schiff bases derived from quinoline-8-carbaldehyde. Synthesis of C-8 substituted quinolines
Oecal,Yolacan,Kaban,Vargas,Kouznetsov
, p. 233 - 236 (2007/10/03)
The Schiff bases derived from quinoline-8-carbaldehyde and substituted aromatic amines were used in the synthesis of C-8 substituted quinolines. 3-Aryl-2-(8-quinolinyl)-4-thiazolidinones were prepared from obtained aldimines by means of the cyclocondensat
