34086-54-9

Upstream product

• 5304-65-4 1-(5-hydroxy-7-methoxy-2,2-dimethyl-chroman-6-yl)-2-(4-methoxy-phenyl)-ethanone 
• 114091-02-0 2-carbethoxy-3(4'-methoxy)phenyl-5-methoxy-8,8-dimethyl-9,10-dihydro-4H,8H-benzo<1,2b:5,6b'>dipyran-4-one 
• 114091-03-1 3-(4'-methoxy)phenyl-5-methoxy-8,8-dimethyl-9,10-dihydro-4H,8H-benzo<1,2b:5,6b'>dipyran-4-one-2-carboxylic acid 
• 97185-33-6 3-(4'-methoxy)phenyl-5-methoxy-8,8-dimethyl-9,10-dihydro-4H,8H-benzo<1,2b:5,6b'>dipyran-4-one 

Relevant academic research and scientific papers

SYNTHESIS OF ALPINUM ISOFLAVONE, DERRONE AND RELATED PYRANOISOFLAVONES

Reaction of phenacylchroman 1 with ethoxyalyl chloride in pyridine followed by hydrolysis of the resulting esters 2 and 3 and decarboxylation of the acids 4 and 5, gave dihydro-4'-O-methyl alpinum isoflavone 6 and 4'-O-methylderrone 7 respectively.Similarly 8 gave 11 which was selectively demethylated to 7.DDQ, dehydrogenation of 6, 7 and 11 gave 14, 15 and 17.Demethylation of 6 and 7 followed by dehydrogenation gave alpinum isoflavone 18 and derrone 19.

THALLIUM(III) NITRATE MEDIATED SYNTHESIS OF ERYTHRININ-A, DIHYDROPYRANO- AND PYRANOISOFLAVONES

Oxidative rearrangement of dihydropyranochalcones using thallium(III) nitrate-trimethylorthoformate (TTN-TMOF) reagent followed by acid catalysed cyclization yields the corresponding dihydropyranoisoflavones in good yields.Dehydrogenation of these isoflavones gave pyranoisoflavones.Demethylation of isoflavone (7) followed by dehydrogenation gave erythrinin-A (16).