340994-68-5

Upstream product

• 14778-29-1 1,1,2,2,-tetracyanoethane 
• 104-87-0 4-methyl-benzaldehyde 
• 868-54-2 1,1,3-tricyano-2-amino-1-propene 

Downstream Products

• 1401792-55-9 C₁₄H₉BrN₄ 
• 1416038-53-3 C₁₄H₉ClN₄ 
• 1586814-51-8 4-amino-8,8-dimethyl-2-methoxy-6-oxo-5-(p-toluyl)-5,6,7,8,9,10-hexahydrobenzo[b][1,8]naphthyridine-3-carbonitrile 
• 1600532-14-6 C₂₀H₁₈N₄O₂*C₄H₁₁N 
• 1600532-29-3 C₁₉H₁₄N₄O₂ 
• 1600532-34-0 5-cyano-6-(dicyanomethylene)-2-methyl-4-(p-tolyl)-1,6-dihydropyridine-3-carboxamide 
• 1600532-39-5 C₂₄H₁₆N₄O 
• 1240096-20-1 C₁₄H₁₀N₄O 

Relevant academic research and scientific papers

Four component DHARMA-synthesis of some densely functionalized 1,8-naphthyridines

We report the one-pot synthesis of the triethylammonium salts of 5,7-diamino-4-aryl-2-(dicyanomethyl)-1,4-dihydro-1,8-naphthyridine-3,6-dicarbonitriles from the reaction of aromatic aldehydes, a malononitrile dimer and triethylamine.

Heterocyclization of michael adducts of β-diketones with arylmethylidene derivatives of malononitrile dimers

Reaction of arylmethylidene derivatives of malononitrile dimer with 1,3-cyclohexanediones in anhydrous methanol in the presence of sodium methylate as catalyst affords 4-amino-5-aryl-2-methoxy-6-oxo-5,6,7,8,9,10- hexahydrobenzo[b][1,8]naphthyridine-3-carb