341035-23-2Relevant academic research and scientific papers
Iron(III) complexation behavior of benzene-centered tripodal mono-, di- and tritopic ligands carrying a repeating -Ahe-(HO)Apr- sequence [Ahe = 6-aminohexanoyl; (HO)Apr = 3-(N-hydroxy)-aminopropanoyl]
Tsubouchi,Shen,Hara,Akiyama
, p. 275 - 282 (2007/10/03)
To investigate how three-directional molecules behave upon complexation with ferric iron, tripodal 1,3,5-benzene-centered mono-, di- and tritopic iron-chelating ligands {C6H3[CO-(Ahe-(HO)Apr)n-OH]3: 1, n = 1; 2, n = 2; 3, n = 3}, composed of strands containing an -Ahe-(HO)Apr- sequence [Ahe = 6-aminohexanoyl; (HO)Apr = 3-(N-hydroxy)aminopropanoyl], were synthesized. These hydroxamate ligands form intramolecular six-coordinate octahedral complexes with Fe(III): Fe1-1, Fe1-2, Fe2-2, Fe1-3, Fe2-3 and Fe3-3. The complexes formed were investigated from a topological viewpoint and examined in terms of stability against attack by H+ and HO-, monoprotonation equilibrium and iron removal kinetics using a 20-molar excess of EDTA. Fe1-1, Fe1-2 and Fe2-2 have tripodal interstrand structures. In particular, the iron removal reaction of Fe2-2 shows a consecutive first-order reaction pattern. From kinetic data of the first-order reactions, Fe1-3, Fe2-3 and Fe3-3 are concluded to possess one, two and three discrete ferrioxamine-type (intrastrand) structures, respectively.
