34129-41-4

Basic information

• Product Name: 6-methoxy-1-[(4-methylphenyl)sulfonyl]-1,2-dihydroquinoline
• CAS NO: 34129-41-4
• Molecular Formula: C₁₇H₁₇NO₃S
• Molecular Weight: 315.3868
• Mol File: 34129-41-4.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 496.9°C at 760 mmHg
• Flash Point: 254.3°C
• Density: 1.27g/cm³
• Vapor Pressure: 5.21E-10mmHg at 25°C
• Refractive Index: 1.617
• CAS DataBase Reference: 6-methoxy-1-[(4-methylphenyl)sulfonyl]-1,2-dihydroquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 6-methoxy-1-[(4-methylphenyl)sulfonyl]-1,2-dihydroquinoline(34129-41-4)
• EPA Substance Registry System: 6-methoxy-1-[(4-methylphenyl)sulfonyl]-1,2-dihydroquinoline(34129-41-4)

Safety Data

• Hazardous Substances Data: 34129-41-4(Hazardous Substances Data)

Upstream product

• 1882-69-5 5-methoxy-2-nitro-benzoic acid 
• 728005-99-0 N-(4-methoxyphenyl)-4-methyl-N-(prop-2-yn-1-yl)benzenesulfonamide 
• 1038502-75-8 6-methoxy-1-tosyl-4-vinyl-1H-benzo[d][1,3]oxazin-2(4H)-one 
• 104-94-9 4-methoxy-aniline 
• 1150-26-1 N-(4-Methoxy-phenyl)-4-methyl-benzenesulfonamide 
• 98-59-9 p-toluenesulfonyl chloride 
• 675578-42-4 N-allyl-N-p-toluenesulfonyl-2-formyl-4-methoxyaniline 
• 675578-40-2 N-p-toluenesulfonyl-5-methoxyanthranilic acid methyl ester 
• 675578-41-3 N-(2-(hydroxymethyl)-4-methoxyphenyl)-4-methylbenzenesulfonamide 
• 6705-03-9 2-Amino-5-methoxybenzoic acid 
• 34159-09-6 N-(2-formyl-4-methoxyphenyl)-4-methylbenzenesulfonamide 
• 2475-80-1 methyl 2-amino-5-methoxybenzoate 
• 402822-76-8 N-allyl-N-p-toluenesulfonyl-2-ethenyl-4-methoxyaniline 
• 333383-73-6 N-(4-methoxy-phenyl)-4-methyl-N-(3-oxo-propyl)-benzenesulfonamide 

Downstream Products

• 5263-87-6 6-methoxy quinoline 

Relevant articles and documents

The Au(I)-catalyzed intramolecular hydroarylation of terminal alkynes under mild conditions: Application to the synthesis of 2H-chromenes, coumarins, benzofurans, and dihydroquinolines

(Chemical Equation Presented) Operationally simple Au(I)-catalyzed intramolecular hydroarylation (IMHA) reactions of terminal alkynes that proceed in high yield and under very mild conditions are described. These processes involve low catalyst loadings, mild reaction temperatures, and short reaction times, require no cocatalysts or additives, and allow for the generation of a number of important heterocyclic motifs from readily accessible starting materials.

Development of isomerization and cycloisomerization with use of a ruthenium hydride with N-heterocyclic carbene and its application to the synthesis of heterocycles

A pure ruthenium hydride complex with N-heterocyclic carbene (NHC) ligand was efficiently generated from the reaction of a second-generation Grubbs ruthenium catalyst with vinyloxytrimethylsilane and unambiguously characterized. This ruthenium hydride complex showed high catalytic activity for the selective isomerization of terminal olefin and for the cycloisomerization of 1,6-dienes. These reactions of N-allyl-o-vinylaniline lead to novel synthetic methods for heterocycles such as indoles and 3-methylene-2,3-dihydroindoles, which are useful synthons for bioactive natural products. These procedures address an important issue in diversity-oriented synthesis.

Selective isomerization of a terminal olefin catalyzed by a ruthenium complex: The synthesis of indoles through ring-closing metathesis

Aruthenium complex, generated from the Grubbs carbene catalyst with vinyloxytrimethylsilane, catalyzed the isomerization of terminal alkenes RCH2-CH=CH2 to internal alkenes RCH=CH-CH3. Application of this olefin isomerization to 2-(N-allylamino)styrene gave the corresponding enamines, which were converted into indoles by a standard ring-closing metathesis, see scheme (Ts = tosyl).