34143-82-3

Usage

Uses

Used in Organic Synthesis:
(E)-N-phenyl-1-(o-tolyl)methanimine is used as a building block for the synthesis of various organic compounds. Its unique structure allows it to be a key component in creating a wide array of chemical products.
Used in Pharmaceutical Production:
In the pharmaceutical industry, (E)-N-phenyl-1-(o-tolyl)methanimine is utilized as a reactive intermediate. It plays a crucial role in the production of various pharmaceuticals, contributing to the development of new medicines and therapeutic agents.
Used in Agrochemicals:
(E)-N-phenyl-1-(o-tolyl)methanimine also finds application in the agrochemical sector, where it is employed in the synthesis of chemicals used in agriculture to enhance crop protection and productivity.
Used in Fine Chemicals:
(E)-N-phenyl-1-(o-tolyl)methanimine is further used in the production of fine chemicals, which are high-purity chemicals used in various specialized applications, including the fragrance, flavor, and specialty chemical industries.
Safety Considerations:
It is important to handle (E)-N-phenyl-1-(o-tolyl)methanimine with care due to potential health risks if not properly managed. Appropriate safety measures should be taken to minimize exposure and ensure the safe use of (E)-N-phenyl-1-(o-tolyl)methanimine in various applications.

Upstream product

• 89-95-2 2-methyl-benzyl alcohol 
• 62-53-3 aniline 
• 529-20-4 2-methylphenyl aldehyde 

Downstream Products

• 62093-68-9 N<(2-Methylphenyl)phenylmethylene>benzenanimine 
• 1018968-25-6 2-(2-methylphenyl)-4-phenylquinoline 
• 10228-78-1 <2,6-Dimethyl-benzyliden>-anilin 
• 1123-56-4 2,6-dimethylbenzaldehyde 

Relevant academic research and scientific papers

Cooperative catalysis of molybdenum with organocatalysts for distribution of products between amines and imines

Multi-amino groups and nitrogen donors compound was discovered as an organocatalyst for N-alkylation of alcohols with amines in the presence of Mo(CO)6. The Mo(CO)6/organocatalyst binary system has shown to be a highly active catalyst for the N-alkylation reaction between alcohols and amines with excellent tolerance of variable starting materials bearing different functional groups. Of particular note, this method possessing a superiority selectivity in the synthesis of N-alkylated amines or imines, which can be controlled by the reaction temperature. The cooperative catalysis mechanism in combination of Mo(CO)6 with organocatalyst was elucidated by control experiments.

A Highly Selective Manganese-Catalyzed Synthesis of Imines under Phosphine-Free Conditions

An efficient and highly selective phosphine-free NN-manganese(I) complex catalyst system was developed for the acceptorless dehydrogenative coupling of alcohols with amines to form imines. The coupling reactions underwent at 3 mol % catalyst loading, and a large range of alcohols and amines with diverse functional groups was applied, including challenging diol and diamine. The target imine products were obtained in good to excellent yields. The present work provides an alternative method to construct highly active nonprecious metal complex catalysts based on phosphine-free ligands.

Fast and efficient synthesis of pyrano[3,2-c]quinolines catalyzed by niobium(V) chloride

A highly efficient two-step method for the synthesis of pyranoquinoline derivatives from imino-Diels-Alder reactions between aldimines and 3,4-dihydro-2H-pyran using niobium(V) chloride as catalyst under mild conditions is described. Georg Thieme Verlag Stuttgart.