341500-92-3Relevant academic research and scientific papers
Screening of a library of 4-aryl/heteroaryl-4H-fused pyrans for xanthine oxidase inhibition: Synthesis, biological evaluation and docking studies
Kaur, Ramandeep,Naaz, Fatima,Sharma, Sahil,Mehndiratta, Samir,Gupta, Manish Kumar,Bedi, Preet Mohinder Singh,Nepali, Kunal
, p. 3334 - 3349 (2015)
A series of 4-aryl/heteroaryl-4H-fused pyrans was synthesized via multicomponent reaction in a microwave synthesizer. All the pyrans were evaluated for in vitro xanthine oxidase inhibition. Structure-activity relationship was also established. Among the s
Catalyst-free green synthesis of tetrahydro-benzo[b]pyrans in magnetized water: experimental aspects and molecular dynamics simulation
Bakherad, Mohammad,Moosavi, Fatemeh,Keivanloo, Ali,Doosti, Rahele,Moradian, Elmira,Armaghan, Mahsa
, p. 2981 - 2997 (2019/02/28)
In this work, magnetized water is applied as a green-promoting medium for the catalyst-free, one-pot, practical, efficient, and environmentally benign multi-component synthesis of tetrahydrobenzo[b]pyrans. Some tetrahydrobenzo[b]pyran derivatives are synt
Efficient synthesis of 2-amino-3-cyano-4H-pyran derivatives via a non-catalytic one-pot three-component reaction
Lü, Cheng-Wei,Wang, Jia-Jing,Li, Fei,Yu, Shi-Jun,An, Yue
, p. 1035 - 1043 (2017/10/07)
Abstract: A convenient one-pot multi-component strategy was conducted successfully under catalyst-free conditions employing water and PEG-400 as the efficient and cheap promoting medium. Three types and nearly 50 2-amino-3-cyano-4H-pyran annulated derivat
Synthesis, screening and docking of fused pyrano[3,2-d]pyrimidine derivatives as xanthine oxidase inhibitor
Kaur, Manroopraj,Kaur, Amandeep,Mankotia, Suhani,Singh, Harbinder,Singh, Arshdeep,Singh, Jatinder Vir,Gupta, Manish Kumar,Sharma, Sahil,Nepali, Kunal,Bedi, Preet Mohinder Singh
, p. 14 - 28 (2017/03/16)
In view of developing effective xanthine oxidase (XO) enzyme inhibitors, a series of 100 pyrano[3,2-d]pyrimidine derivatives was synthesized and evaluated for its in vitro XO enzyme inhibition. Structure activity relationship has also been established. Am
4-Dialkylaminopyridine modified magnetic nanoparticles: As an efficient nano-organocatalyst for one-pot synthesis of 2-amino-4: H -chromene-3-carbonitrile derivatives in water
Dangolani, Soheila Khajeh,Panahi, Farhad,Nourisefat, Maryam,Khalafi-Nezhad, Ali
, p. 92316 - 92324 (2016/10/09)
A novel heterogeneous magnetic nano-organocatalyst was developed using immobilization of 4-dialkylaminopyridine moieties on Fe3O4 magnetic nanoparticles (MNP-DMAP). It was synthesized using the reaction of MNP-oxiran (MNPO) with N-methylpyridin-4-amine. The MNPO substrate was produced via oxidation of vinyl groups on the surface of vinyl-functionalized MNP (VMNP) using H2O2. To synthesis VMNP, silica-coated magnetic nanoparticles (Fe3O4@SiO2) were reacted with trimethoxy(vinyl)silane. The MNP-DMAP catalyst shows remarkable activity in the synthesis of 2-amino-4H-chromene-3-carbonitrile derivatives using a multicomponent reaction under mild conditions in water as a green solvent. The MNP-DMAP was reusable in this process for at least 10 times without any treatment in its catalytic activity.
