341524-25-2Relevant academic research and scientific papers
The first synthesis of enantiopure α-amino ketimines and amino aziridines
Concellon,Bernad,Riego,Garcia-Granda,Forcen-Acebal
, p. 2764 - 2768 (2001)
Chiral 1-aminoalkyl chloromethyl ketimines 2 are synthesized in enantiomerically pure form starting from 1-aminoalkyl chloromethyl ketones 1 and different amines. Reduction of amino ketimines 2 and subsequent spontaneus cyclization affords aminoalkyl aziridines 3 with high diastereoisomeric excess and without detectable racemization.
