341548-07-0

Basic information

• Product Name: 2-formyl-8-methoxy-5-phenylsulfanyl-2,3,4,5-tetrahydro-1H-2-benzazepine
• Synonyms: 2-formyl-8-methoxy-5-phenylsulfanyl-2,3,4,5-tetrahydro-1H-2-benzazepine
• CAS NO: 341548-07-0
• Molecular Weight: 313.42
• Mol File: 341548-07-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-formyl-8-methoxy-5-phenylsulfanyl-2,3,4,5-tetrahydro-1H-2-benzazepine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-formyl-8-methoxy-5-phenylsulfanyl-2,3,4,5-tetrahydro-1H-2-benzazepine(341548-07-0)
• EPA Substance Registry System: 2-formyl-8-methoxy-5-phenylsulfanyl-2,3,4,5-tetrahydro-1H-2-benzazepine(341548-07-0)

Safety Data

• Hazardous Substances Data: 341548-07-0(Hazardous Substances Data)

Upstream product

• 341547-95-3 N-(3-methoxyphenyl)methyl-N-[(3-phenylsulfanyl)propyl]formamide 
• 341547-88-4 N-(3-methoxyphenyl)methyl-(3-phenylsulfanyl)propylamine 
• 591-31-1 3-methoxy-benzaldehyde 
• 341548-01-4 N-(3-methoxyphenyl)methyl-N-[(3-phenylsulfinyl)propyl]formamide 
• 2015-09-0 3-(phenylthio)propylamine 

Downstream Products

• 247133-22-8 8-Methoxy-2,3,4,5-tetrahydro-1H-benz[c]azepine 

Relevant articles and documents

Synthesis of 2,3,4,5-tetrahydro-1H-2-benzazepines via Pummerer-type cyclization of N-arylmethyl-N-(3-phenylsulfinylpropyl) formamides

A construction of 1H-benzazepine ring system was achieved via a modified Pummerer reaction of N-arylmethyl-N-(3-phenylsulfinylpropyl)-formamides (5) using trifluoroacetic acid and borontrifluoride etherate. This method provides an effective synthesis of 7,8-dimethoxy-2,3,4,5-tetrahydro-1H-2-benzazepine (10a), the synthetic intermediate of capsazepine (1), an antagonist of capsaicin and resinferatoxin.