34160-16-2

Basic information

• Product Name: 3,5-dimethyl-N-p-tolylbenzenamine
• Synonyms: 3,5-dimethyl-N-p-tolylbenzenamine
• CAS NO: 34160-16-2
• Molecular Weight: 211.307
• Mol File: 34160-16-2.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 3,5-dimethyl-N-p-tolylbenzenamine(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-dimethyl-N-p-tolylbenzenamine(34160-16-2)
• EPA Substance Registry System: 3,5-dimethyl-N-p-tolylbenzenamine(34160-16-2)

Safety Data

• Hazardous Substances Data: 34160-16-2(Hazardous Substances Data)

Upstream product

• 106-38-7 para-bromotoluene 
• 108-69-0 3,5-dimethylaminoaniline 
• 106-43-4 para-chlorotoluene 
• 120-72-9 indole 
• 556-96-7 5-bromo-1,3-xylene 
• 19311-91-2 N,N-diethylsalicylamide 
• 106-49-0 p-toluidine 
• 62-53-3 aniline 
• 99-12-7 5-nitro-m-xylene 
• 99-99-0 1-methyl-4-nitrobenzene 
• 172975-69-8 3,5-dimethylphenyl boronic acid 

Relevant articles and documents

Electrochemical Reductive Arylation of Nitroarenes with Arylboronic Acids

The synthesis of diarylamine is extremely important in organic chemistry. Herein, a novel electrochemical reductive arylation of nitroarenes with arylboronic acids was developed. A variety of diarylamines were synthesized without the need for transition-metal catalysts. The reaction could be scaled up efficiently in a flow cell and several derivatization reactions were carried out smoothly. Cyclic voltammetry experiments and mechanism studies showed that acetonitrile, formic acid, and triethyl phosphite all played a role in promoting this reductive arylation transformation.

Buchwald-Hartwig amination of (hetero)aryl chlorides by employing Mor-DalPhos under aqueous and solvent-free conditions

We report on the application of the [Pd(cinnamyl)Cl]2/Mor- DalPhos catalyst system in the Buchwald-Hartwig amination of (hetero)aryl chlorides with primary or secondary amines conducted either under aqueous conditions without the use of co-solvents and/or surfactants or under solvent-free conditions (52 examples). We have established that reactions of this type can be conducted without the rigorous exclusion of air, and in the case of the solvent-free reactions, we have demonstrated that appropriately selected liquid and solid reagents can be employed successfully.

Efficient iron/copper cocatalyzed N-arylation of arylamines with bromoarenes

Fe(acac)3 and Cu(OAc)2H2O were found to effectively promote the C-N cross-coupling reaction in the presence of K 2CO3 as the base. A series of diaryl amine with different substituents can be synthesized in moderate to good yields. This efficient and economic method is attractive for applications on an industrial scale. Georg Thieme Verlag Stuttgart - New York.