34165-09-8

Basic information

• Product Name: 2-METHYL-3-NITROIMIDAZO[1,2-A]PYRIDINE
• Synonyms: 2-METHYL-3-NITROIMIDAZO[1,2-A]PYRIDINE
• CAS NO: 34165-09-8
• Molecular Formula: C₈H₇N₃O₂
• Molecular Weight: 177.16
• Product Categories: Fused Ring Systems
• Mol File: 34165-09-8.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-METHYL-3-NITROIMIDAZO[1,2-A]PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-METHYL-3-NITROIMIDAZO[1,2-A]PYRIDINE(34165-09-8)
• EPA Substance Registry System: 2-METHYL-3-NITROIMIDAZO[1,2-A]PYRIDINE(34165-09-8)

Safety Data

• Hazardous Substances Data: 34165-09-8(Hazardous Substances Data)

Usage

General Description

2-Methyl-3-nitroimidazo[1,2-a]pyridine is a chemical compound that belongs to the nitroimidazole class of compounds. It is a yellow crystalline solid with a molecular formula of C7H6N4O2 and a molecular weight of 182.14 g/mol. 2-METHYL-3-NITROIMIDAZO[1,2-A]PYRIDINE is used in the pharmaceutical industry as a precursor for the synthesis of various pharmacologically active compounds, including antiprotozoal and antibacterial agents. It has also been studied for its potential use in the treatment of cancer, due to its ability to bind to DNA and exhibit cytotoxic properties. Additionally, 2-Methyl-3-nitroimidazo[1,2-a]pyridine has been investigated for its use as a sensitizing agent in radiation therapy. However, it is important to note that this compound may pose health and environmental hazards, and proper safety precautions should be observed when handling and using it.

Upstream product

• 934-37-2 2-methylimidazo[1,2-a]pyridine 

Downstream Products

• 406207-66-7 N-(2-methyl-imidazo[1,2-a]pyridin-3-yl)-benzamide 
• 857350-33-5 3-amino-2-formylimidazo[1,2-a]pyridine 
• 28036-31-9 3-amino-2-methylimidazo[1,2-a]pyridine 
• 4926-45-8 3-nitro-imidazo[1,2-a]pyridine 
• 429690-60-8 3-nitroimidazo[1,2-a]pyridine-2-carbaldehyde 

Relevant articles and documents

New pyrazole derivatives as CRAC channel modulators

The present invention relates to compounds of formula (I) which are inhibitors of CRAC channel activity. This invention also relates to pharmaceutical compositions containing them, process for their preparation and their use in therapy.

3-Benzamido, ureido and thioureidoimidazo[1,2-a]pyridine derivatives as potential antiviral agents

This work reports the synthesis and the antiviral activities of 3-benzamido, 3-phenylureido and 3-phenylthioureido derivatives in the imidazo[1,2-a]pyridine series. The structure was proven by NMR spectroscopy. The synthesized compounds were evaluated against a large number of viruses. The 3-phenylthioureido derivative 7 showed moderate activity against human cytomegalovirus (HCMV) in vitro. The crystallographic data for 8 are also reported and explain the absence of activity against human immunodeficiency virus (HIV).