34175-96-7

Usage

Uses

Used in Pharmaceutical Industry:
(2R)-Pterosin B is used as a pharmaceutical agent for its cytotoxic properties, which can be harnessed to target and kill cancer cells. Its potential as an anticancer compound is under extensive research, particularly for its ability to inhibit the growth of various types of cancer cells.
Used in Antimicrobial Applications:
(2R)-Pterosin B is used as an antimicrobial agent for its antifungal and antibacterial properties, making it a candidate for the development of new antibiotics and antifungal medications to combat drug-resistant infections.
Used in Research and Development:
(2R)-Pterosin B is utilized in research and development for its potential applications in medicine and its impact on human and animal health. Ongoing studies aim to understand its mechanisms of action, optimize its therapeutic potential, and mitigate its potential carcinogenic effects when consumed in high amounts.

InChI:InChI=1/C14H18O2/c1-8-6-11-7-9(2)14(16)13(11)10(3)12(8)4-5-15/h6,9,15H,4-5,7H2,1-3H3/t9-/m1/s1

Upstream product

• 1008099-10-2 (2R)-pterosin B 14-O-β-(4'-p-coumaroyl)-glucopyranoside 
• 87625-62-5 ptaquiloside 
• 63-68-3 L-methionine 

Downstream Products

• 34169-69-2 pterosin Z 
• 35944-01-5 6-<2-methoxyethyl>-2,2,5,7-tetramethylindan-1-one 
• 29774-74-1 (2R)-pterosin B 14-O-β-D-glucopyranoside 
• 39815-60-6 palmitylpterosin B 
• 52528-78-6 pterosin E 

Relevant academic research and scientific papers

Cytotoxic diterpenoids and sesquiterpenoids from Pteris multifida

Three new ent-kaurane diterpenoids, named pterokaurane M1-M 3 (1-3) and three new C14 pterosin-sesquiterpenoids, named multifidoside A-C (4-6), along with 18 known compounds, were isolated from the whole plants of Pteris multifida. The structures of 1-6 were established using spectroscopic methods, including extensive 2D NMR and CD analyses. Compounds 4 and 5 showed cytotoxicity against the HepG2 tumor cell line with IC50 values of less than 10 μM.

PTAQUILOSIDE, A POTENT CARCINOGEN ISOLATED FROM BRACKEN FERN PTERIDIUM AQUILINUM VAR. LATIUSCULUM: STRUCTURE ELUCIDATION BASED ON CHEMICAL AND SPECTRAL EVIDENCE, AND REACTIONS WITH AMINO ACIDS, NUCLEOSIDES, AND NUCLEOTIDES

The structure of ptaquiloside (I), a potent carcinogenic compound isolated from bracken fern, Pteridium aquilinum var. latiusculum has been elucidated on the basis of chemical and spectral evidence.The dienone 3 generated from 1 under alkaline conditions was shown to be a strong alkylating agent.For the purpose of obtaining the preliminary information on chemical modification of biopolymers such as proteins and DNA with the dienone 3, reactions of 3 with amino acids, nucleosides, and nucleotides have been carried out and the alkylated products have been characterized.