34184-77-5 Usage
Description
Promegestone, also known by its brand name Surgestone, is a potent progestin that closely resembles the hormone progesterone. It is characterized by its 17beta-propionylestra-4,9-dien-3-one structure, with a methyl group substitution at position 17. Promegestone is unique in that it does not possess androgenic properties, which means it does not cause masculinizing side effects. This characteristic makes it particularly useful in the treatment of various gynecological conditions.
Uses
Used in Gynecological Applications:
Promegestone is used as a hormone replacement therapy for the treatment of gynecological conditions resulting from luteal insufficiency. These conditions include premenopausal disorders, dysmenorrhea, and premenstrual syndrome. Its progesterone-like action helps to alleviate symptoms and restore hormonal balance in affected individuals.
Used in Pharmaceutical Research:
Promegestone is also utilized as a radioligand for the progestin receptor in pharmaceutical research. This application allows scientists to study the interactions between the progestin receptor and various compounds, which can lead to the development of new treatments for conditions related to hormonal imbalances.
Originator
Roussel (France)
Check Digit Verification of cas no
The CAS Registry Mumber 34184-77-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,4,1,8 and 4 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 34184-77:
(7*3)+(6*4)+(5*1)+(4*8)+(3*4)+(2*7)+(1*7)=115
115 % 10 = 5
So 34184-77-5 is a valid CAS Registry Number.
InChI:InChI=1/C22H30O2/c1-4-20(24)22(3)12-10-19-18-7-5-14-13-15(23)6-8-16(14)17(18)9-11-21(19,22)2/h13,18-19H,4-12H2,1-3H3/t18-,19+,21+,22-/m1/s1