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N-(1-Hydroxy-1-trifluoromethyl-2,2,2-trifluoroethyl)aniline is a complex organic compound with the molecular formula C9H5F6NO. It is characterized by the presence of an aniline group (C6H5NH2), which is attached to a unique trifluoroethyl moiety. This moiety features a hydroxyl group (-OH), a trifluoromethyl group (-CF3), and two additional fluorine atoms, making the entire side chain highly fluorinated. The compound is known for its potential applications in the synthesis of pharmaceuticals and agrochemicals, particularly due to its reactivity and the influence of fluorine atoms on its physical and chemical properties. The presence of fluorine can significantly alter the compound's lipophilicity, metabolic stability, and binding affinity, which are crucial factors in drug design.

3420-86-8

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3420-86-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 3420-86-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,4,2 and 0 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 3420-86:
(6*3)+(5*4)+(4*2)+(3*0)+(2*8)+(1*6)=68
68 % 10 = 8
So 3420-86-8 is a valid CAS Registry Number.

3420-86-8Relevant academic research and scientific papers

REACTIONS OF HIGHLY ELECTROPHILIC POLYFLUOROCARBONYL COMPOUNDS WITH PRIMARY ARYLAMINES

Chkanikov, N. D.,Sviridov, V. D.,Zelenin, A. E.,Galakhov, M. V.,Kolomiets, A. F.,Fokin, A. V.

, p. 323 - 328 (1990)

C-Hydroxyalkylation of primary arylamines by highly electrophilic polyfluorocarbonyl compounds results from the direct reaction of the initial reagents and is competitively inhibited by equilibrium N-hydroxyalkylation.The presence of steric hindrances to

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