342385-23-3Relevant academic research and scientific papers
Imidazo[1,2-a]benzimidazole derivatives: XXIX. 1-Allyl-2-amino-3- acylmethylbenzimidazolium halides and syntheses on their base
Anisimova,Tolpygin
, p. 1354 - 1361 (2011/12/05)
Cyclization of 1-allyl-2-amino-3-acylmethylbenzimidazolium halides under alkaline conditions gave 9-allyl-substituted imidazo[1,2-a]benzimidazoles. Cyclization of the same compounds on heating in concentrated hydrobromic acid was accompanied by addition o
Compounds capable of modulating the activity of multidrug transporters and therapeutic use of the same
-
, (2008/06/13)
Methods of modulating the activity of multidrug transporters are disclosed. The methods of modulating the activity of multidrug transporters use compounds that selectively increase or decrease the efflux capabilities of the multidrug transporter. The methods can be used therapeutically to enhance performance of therapeutic drugs, like chemotherapeutic drugs and antibiotics; to promote detoxification of cells and tissues; and to increase or decrease the efficacy of the blood-brain barrier or placental barrier.
