342402-77-1

Usage

Chemical structure

Derived from cyclohexanone with a highly reactive acyl chloride group.

Reactivity

Reactive acyl chloride that can be used for various synthetic reactions.

Uses

Utilized in organic synthesis as a key intermediate for the production of pharmaceuticals, agrochemicals, and other fine chemicals. Also used in the preparation of carboxylic acid derivatives and amides.

Handling and storage

Must be handled and stored with caution and proper safety measures due to its reactivity.

Upstream product

• 1438-96-6 (2-oxocyclohexyl)acetic acid 
• 24731-17-7 ethyl 2-(2-oxocyclohexyl)acetate 

Downstream Products

• 303155-40-0 3-oxo-4-(2-oxo-cyclohexyl)-butyric acid ethyl ester 
• 1233241-59-2 methyl 1-[(2-oxocyclohexyl)acetyl]-1H-indole-3-carboxylate 
• 303155-07-9 2-diazo-4-(2-oxocyclohexyl)-3-oxobutanoic acid ethyl ester 
• 303155-08-0 1-diazo-3-(2-oxocyclohexyl)propan-2-one 

Relevant academic research and scientific papers

Highly diastereoselective samarium diiodide induced ketyl cyclisations of indole and pyrrole derivatives - Scope and limitations

Here we summarise our results for SmI2-induced 5-exo-trig to 8-exo-trig reductive cyclisations of suitably substituted indole and pyrrole derivatives. All precursors were easily prepared by simple N-alkylation or N-acylation of indole and pyrro

Facile synthesis of oxatricyclic systems with various ring sizes and substituents

A series of α-diazo carbonyl compounds having cyclopentanone, cyclohexanone and substituted cyclohexanone units with different tether lengths have been synthesized using diazomethane solution or methanesulphonyl azide. The above synthesized α-diazo carbon