342403-52-5

Basic information

• Product Name: <2-hydroxy-2-phenyl-2-(2-pyridyl)ethyl>methylsulfoxide
• Synonyms: <2-hydroxy-2-phenyl-2-(2-pyridyl)ethyl>methylsulfoxide
• CAS NO: 342403-52-5
• Molecular Weight: 261.345
• Mol File: 342403-52-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: <2-hydroxy-2-phenyl-2-(2-pyridyl)ethyl>methylsulfoxide(CAS DataBase Reference)
• NIST Chemistry Reference: <2-hydroxy-2-phenyl-2-(2-pyridyl)ethyl>methylsulfoxide(342403-52-5)
• EPA Substance Registry System: <2-hydroxy-2-phenyl-2-(2-pyridyl)ethyl>methylsulfoxide(342403-52-5)

Safety Data

• Hazardous Substances Data: 342403-52-5(Hazardous Substances Data)

Upstream product

• 101-82-6 2-Benzylpyridine 
• 67-68-5 dimethyl sulfoxide 
• 5005-36-7 phenyl-pyridin-2-yl-acetonitrile 
• 627-30-5 1-chloro-3-hydroxypropane 
• 91-02-1 phenyl(pyridin-2-yl)methanone 

Relevant articles and documents

Transition-Metal Free Chemoselective Hydroxylation and Hydroxylation-Deuteration of Heterobenzylic Methylenes

We developed an approach for direct selective hydroxylation of heterobenzylic methylenes to secondary alcohols avoiding overoxidation to ketones by using a KOBu-t/DMSO/air system. Most reactions could reach completion in several minutes to give hydroxylated products in 41-76% yields. Using DMSO-d6, this protocol resulted in difunctionalization of heterobenzylic methylenes to afford α-deuterated secondary alcohols (>93% incorporation). By employing this method, active pharmaceutical ingredients carbinoxamine and doxylamine were synthesized in two steps in moderate yields.