34243-38-4

Usage

Uses

Used in Research Applications:
Benzothiazole, 2-(2-thienyl)(8CI,9CI) is used as a research tool for [application reason] in the field of [specific research area or industry]. Its unique chemical structure and properties make it valuable for studying various chemical reactions and processes.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Benzothiazole, 2-(2-thienyl)(8CI,9CI) is used as a [specific application type, e.g., intermediate, building block, or active pharmaceutical ingredient] for [application reason, e.g., the development of new drugs or the synthesis of complex organic molecules].
Used in Chemical Synthesis:
Benzothiazole, 2-(2-thienyl)(8CI,9CI) is used as a key intermediate or building block in the synthesis of various organic compounds, particularly those with potential applications in materials science, agrochemicals, or other specialized fields.

InChI:InChI=1/C11H7NS2/c1-2-5-9-8(4-1)12-11(14-9)10-6-3-7-13-10/h1-7H

Upstream product

• 105-64-6 diisopropyl peroxydicarbonate 
• 142505-41-7 N-(2-thienylmethylene)-2-methylthiobenzenamine 
• 142505-36-0 N-(2-thienylmethylene)-2-phenylthiobenzenamine 
• 1003-31-2 thiophene-2-carbonitrile 
• 137-07-5 2-amino-benzenethiol 
• 39582-59-7 benzothiazol-2-yl-lithium 

Downstream Products

• 380431-21-0 2-(5'-carboxy-2'-thienyl)benzothiazole 
• 1260371-36-5 2-[5'-(para-fluorobenzoyl)-2'-thienyl]benzothiazole 
• 1260371-35-4 2-(5'-benzoyl-2'-thienyl)benzothiazole 
• 1260371-37-6 2-[5'-(para-nitrophenyl)-2'-thienyl]benzothiazole 

Relevant academic research and scientific papers

ZnO-NPs catalyzed condensation of 2-aminothiophenol and aryl/alkyl nitriles: Efficient green synthesis of 2-substituted benzothiazoles

The synthesis of 2-substituted benzothiazoles has been described using ZnO-nanoparticles as a catalyst. The condensation of 2-aminothiophenol and aryl/alkyl nitriles resulted in the formation of various 2-substituted benzothiazoles under solvent-free reaction conditions. The library of 2-substituted benzothiazoles has been synthesized in good to excellent yield. The reaction has shown a wide range of functional group compatibility for both varyingly substituted 2-aminothiophenols and nitriles. The protocol has many advantages such as faster reaction rate, mild reaction conditions, various functional group compatibility, excellent yield, solvent-free reaction conditions, easy recovery of materials, and excellent catalyst recyclability, among others. The various advantages of this protocol make it a more feasible, economical, and environmentally benign process.

Syntheses of 2-arylbenzothiazoles from flash vacuum pyrolyses and photolyses of 2-methylthio-N-(arenylidene)anilines

Flash vacuum pyrolyses and photolyses of 2-methylthio-N-(arenylidene)anilines 2a-h are new and convenient methods for the syntheses of 2-arylbenzothiazoles 1a-h.

Inter- and Intramolecular Biaryl Couplings Via Cyanocuprate Intermediates

Low temperature oxidations of selected higher order cyanocuprates composed of one or two heteroaromatic ligands can be oxidatively coupled in an inter- or intramolecular fashion to afford unsymmetrical biaryls.Non-heteroaromatic systems have also been studied in related intramolecular processes.

The reaction of (2-alkylidenaminophenyl)sulfides with di-iso-propyl peroxydicarbonate: Radical versus non-radical pathway

The reaction of 2-methylthio- or 2-phenylthioarylimines with di-iso-propyl peroxydicarbonate (DPDC) is described. The phenylthio-derivatives undergo cyclization to benzothiazoles via a free-radical mechanism, whereas the methylthio-analogs afford arylthiomethyl iso-propyl carbonates, together with benzothiazoles as well; this last result could be accounted for with the intervention of a non-radical mechanism operating side by side with the radical one.