342603-75-2

Upstream product

• 342600-38-8 4-(1-furo[3,2-c]pyridin-2-yl-1-methyl-ethyl)-2-(3,3,3-trifluoro-propylcarbamoyl)-piperazine-1-carboxylic acid tert-butyl ester 
• 342603-71-8 4-[1-(7-iodo-furo[3,2-c]pyridin-2-yl)-1-methyl-ethyl]-piperazine-1,2-dicarboxylic acid 2-benzyl ester 1-tert-butyl ester 
• 342600-22-0 4-[1-(7-iodo-furo[3,2-c]pyridin-2-yl)-1-methyl-ethyl]-piperazine-2-carboxylic acid benzyl ester 
• 342600-17-3 piperazine-1,2,4-tricarboxylic acid 1-allyl ester 2-benzyl ester 4-tert-butyl ester 
• 342600-19-5 (S)-4-(1,1-Dimethyl-prop-2-ynyl)-piperazine-1,2-dicarboxylic acid 1-allyl ester 2-benzyl ester 
• 342600-23-1 4-(1-furo[3,2-c]pyridin-2-yl-1-methyl-ethyl)-piperazine-1,2-dicarboxylic acid 1-tert-butyl ester 
• 342600-20-8 (S)-Piperazine-1,2-dicarboxylic acid 1-allyl ester 2-benzyl ester 
• 1111-97-3 3-chloro-3-methylbut-1-yne 
• 7153-08-4 4-hydroxy-3,5-diiodopyridine 
• 342600-31-1 (3aS,9bS)-1-{(2R)-2-benzyl-3-[(2S)-oxiran-2-yl]propanoyl}-2,2-dimethyl-1,3a,4,9b-tetrahydro-2H-chromeno[4,3-d][1,3]oxazole 
• 342600-39-9 4-(1-furo[3,2-c]pyridin-2-yl-1-methyl-ethyl)-piperazine-2-carboxylic acid (3,3,3-trifluoro-propyl)-amide 

Relevant academic research and scientific papers

Synthesis and activity of novel HIV protease inhibitors with improved potency against multiple PI-resistant viral strains.

Substitution of the t-butylcarboxamide substituent in analogues of the HIV protease inhibitor (PI) Indinavir with a trifluoroethylamide moiety confers greater potency against both the wild-type (NL4-3) virus and PI-resistant HIV. The trifluoroethyl substi