342634-35-9Relevant academic research and scientific papers
2-arylquinoline derivatives, preparation and therapeutic use thereof
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, (2008/06/13)
Compounds of general formula (I) in which: A represents a hydrogen atom, a hydroxyl, a C1-3alkoxy group, a hydroxy(C1-6alkyl) group, a (C1-3alkoxy)(C1-3alkyl) group, a thiol, (C1-6alkyl)sulfanyl or a halogen; B and D represent, independently of one another, a hydrogen atom, a C1-6alkyl group, a fluoro(C1-6alkyl) group or a perfluoro(C1-2alkyl) group or B and D together from an oxo; R1represents a phenyl, a naphthyl or a heteroaryl comprising 4 or 5 carbon atoms; R2and R3represent, independently of one another, a hydrogen atom, a halogen or a C1-6alkyl group, R4represents a hydrogen atom, a hydroxyl or a halogen, and R5and R6represent, independently of one another, a hydrogen atom, a C1-6alkyl group, a C2-6alkenyl group, a C3-6cycloalkyl group, a C3-6cycloalkenyl group, a fluoro(C1-6alkyl) group or a perfluoro(C1-2alkyl) group or R5and R6together form a C2-6alkylene chain or a C3-6alkenylene chain, to give, with the nitrogen to which they are attached, a heterocycle, this heterocycle optionally being substituted by a C1-4alkyl group; and their salts.
