342652-78-2

Upstream product

• 114908-93-9 3-(1,1-dimethyleth-1-yl)-4-hydroxy-2(5H)-furanone 

Downstream Products

• 265643-78-5 4-tert-butyl-3-(hydroxymethyl)-1H-pyrazol-5-yl 4-methylbenzenesulfonate 
• 342652-80-6 3-tert-butyl-7-(5-methylisoxazol-3-yl)-2-[(4-methylphenyl)sulphonyloxy]pyrazolo[1,5-d][1,2,4]triazine 
• 783331-24-8 3-tert-butyl-7-(5-methylisoxazol-3-yl)-2-(1-methyl-1H-1,2,4-triazol-5-ylmethoxy)pyrazolo[1,5-d][1,2,4]triazine 
• 265643-79-6 4-tert-butyl-5-formyl-3-[(4-methylphenyl)sulphonyloxy]pyrazole 

Relevant academic research and scientific papers

An orally bioavailable, functionally selective inverse agonist at the benzodiazepine site of GABAA α5 receptors with cognition enhancing properties

(3-tert-Butyl-7-(5-methylisoxazol-3-yl)-2-(1-methyl-1H-1,2, 4-triazol-5-ylmethoxy)pyrazolo[1,5-d][1,2,4]triazine (13) has been identified as a functionally selective, inverse agonist at the benzodiazepine site of GABAA α5 receptors. 13 is orall

Substances for treatment or relief of pain

Disclosed is the use of an inverse agonist for alpha-subunit-containing gamma-aminobutyric acid A receptor in the preparation of a medicine for the prevention, alleviation, or treatment of pain.