34272-02-1Relevant articles and documents
Design, synthesis, and biological evaluation of a highly water-soluble psoralen-based photosensitizer
Uruma, Yoshiyuki,Nonomura, Takuya,Yen, Priscilla Yoong Mei,Edatani, Marie,Yamamoto, Ryotaro,Onuma, Kunishige,Okada, Futoshi
, p. 2372 - 2377 (2017)
In recent years, photodynamic therapy (PDT) has been approved for treating various medical conditions, including cancer. PDT is a treatment that employs a particular drugs, called photosensitizers which work along with specific light source. The growth of this medical industry is expanding as it is another promising alternative to treat cancer which lessen the burden of treatments in patients. This includes the benefits of minimally invasive procedures and delivering high accuracy in targeting mutations. In recent two decades, cancer researchers have produced remarkable studies on developing photosensitizers that enhance understanding of biology and genetics of cancer. It is unfortunate that not all PDT can work as well as other profound treatment because PDT has various limitations like PDT leads photosensitivity reaction that arises when the photosensitizer remains in the body for a long period of time. In this paper, our studies centers on synthesizing a highly soluble photosensitizing agent with improved effectiveness on detecting cancer cells.
Some reactions of 2-propynyl glycosides
Horisberger,Lewis,Smith
, p. 144 - 147 (1972)
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A highly efficient and selective synthesis of 1,2,3-triazole linked saccharide nucleosides via "click chemistry"
Ding, Haixin,Yang, Ruchun,Song, Yang,Xiao, Qiang,Wu, Jun
, p. 368 - 375 (2008)
A series of 1,2,3-triazole linked saccharide nucleosides were synthesized in high yield and selectivity via "click chemistry" of the 3'-azido-2'-deoxythymidine and the propargyl carbohydrates. (Chemical Presented). Copyright Taylor & Francis Group, LLC.
Copper-catalyzed one-pot synthesis of glycosylated iminocoumarins and 3-triazolyl-2-iminocoumarins
Mandal, Pintu Kumar
, p. 5803 - 5814 (2014)
A general strategy was developed for the synthesis of glycosyl iminocoumarins (5a-x) in a one-pot, copper-catalyzed multicomponent reaction involving a domino reaction of sulfonyl azides, sugar alkynes, and salicylaldehydes via ketenimine intermediate for
Fluorescent sugar and uridine conjugates of 1,8-naphthalimides with methyl and ferrocenyl headgroups
Cavigiolio, Giorgio,Morgan, Joy L.,Robinson, Brian H.,Simpson, Jim
, p. 885 - 894 (2004)
The first amphiphilic sugar and deoxyuridine conjugates with a 4-ethynyl-1,8-N-methylnaphthalimide linker, a 4-ethynyldeoxyuridine conjugate with a N-undecylferrocenyl headgroup, and a 1,8-naphthalimide with a 2,3,4,6-tetra-O-acetate-β-D-glucopyranoside h
Synthesis of functionalized copillar[4+1]arenes and rotaxane as heteromultivalent scaffolds
Chen, Wenzhang,Mohy Ei Dine, Tharwat,Vincent, Stéphane P.
supporting information, p. 492 - 495 (2021/01/25)
In this study, novel copillar[4+1]arenes were used as central heteromultivalent scaffolds via orthogonal couplings with a series of biologically relevant molecules such as carbohydrates, α-amino acids, biotin and phenylboronic acid. Further modifications by introducing maleimides or cyclooctyne groups provided molecular probes adapted to copper-free click chemistry. An octa-azidated fluorescent rotaxane bearing two distinct ligands was also generated in a fully controlled manner.
Exploring the Biochemical Foundations of a Successful GLUT1-Targeting Strategy to BNCT: Chemical Synthesis and in Vitro Evaluation of the Entire Positional Isomer Library of ortho-Carboranylmethyl-Bearing Glucoconjugates
Matovi?, Jelena,J?rvinen, Juulia,Sokka, Iris K.,Imlimthan, Surachet,Raitanen, Jan-Erik,Montaser, Ahmed,Maaheimo, Hannu,Huttunen, Kristiina M.,Per?niemi, Sirpa,Airaksinen, Anu J.,Sarparanta, Mirkka,Johansson, Mikael P.,Rautio, Jarkko,Ekholm, Filip S.
, p. 285 - 304 (2020/12/21)
Boron neutron capture therapy (BNCT) is a noninvasive binary therapeutic modality applicable to the treatment of cancers. While BNCT offers a tumor-targeting selectivity that is difficult to match by other means, the last obstacles preventing the full har
