34272-09-8

Basic information

• Product Name: 1,2,3,9,10-pentamethoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline
• CAS NO: 34272-09-8
• Molecular Formula: C₂₁H₂₅NO₅
• Molecular Weight: 371.4269
• Mol File: 34272-09-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 526.3°C at 760 mmHg
• Flash Point: 220.4°C
• Density: 1.183g/cm³
• Vapor Pressure: 3.64E-11mmHg at 25°C
• Refractive Index: 1.567
• CAS DataBase Reference: 1,2,3,9,10-pentamethoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2,3,9,10-pentamethoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline(34272-09-8)
• EPA Substance Registry System: 1,2,3,9,10-pentamethoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline(34272-09-8)

Safety Data

• Hazardous Substances Data: 34272-09-8(Hazardous Substances Data)

Usage

Chemical class

Tetrahydroisoquinoline alkaloid

Molecular structure

Contains five methoxy groups

Pharmacological properties

Studied for potential antineoplastic and anti-inflammatory activities

Research significance

Potentially valuable target for chemical synthesis and medicinal chemistry research

Structure-activity relationship

Unique structure and potential biological activities make it a valuable tool for investigating the structure-activity relationship of tetrahydroisoquinoline alkaloids and related compounds

Applications

May be used in the development of new drugs targeting cancer and inflammation

Synthesis

Complex chemical synthesis process required to produce the compound

Stability

May require specific storage conditions to maintain its stability and potency

Solubility

Solubility properties may affect its formulation and administration in potential drug development

Toxicity

Further research needed to determine the safety and potential side effects of the compound in biological systems

Upstream product

• 959856-45-2 N-formyl purpureine 

Relevant articles and documents

Application of the hypervalent iodine reagent to the synthesis of some pentasubstituted aporphine alkaloids

The oxidative biaryl coupling of various N-substituted 1- benzyltetrahydroisoquinolines to the corresponding aporphines by the hypervalent iodine reagent was studied. The study sheds light on the unifying mechanism of the reaction illustrating the requirement of the p-p coupling via the six-membered transition state as the initial step. The finding was applied to the synthesis of some pentasubstituted aporphine alkaloids. Georg Thieme Verlag Stuttgart.