34274-05-0

Basic information

• Product Name: Morpholine, 4-[(3,4,5-trimethoxyphenyl)methyl]-
• Synonyms: 4-(3,4,5-Trimethoxy-benzyl)-morpholine
• CAS NO: 34274-05-0
• Molecular Formula: C14H21NO4
• Molecular Weight: 267.325
• Mol File: 34274-05-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 359.1±37.0 °C(Predicted)
• Density: 1.119±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Morpholine, 4-[(3,4,5-trimethoxyphenyl)methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Morpholine, 4-[(3,4,5-trimethoxyphenyl)methyl]-(34274-05-0)
• EPA Substance Registry System: Morpholine, 4-[(3,4,5-trimethoxyphenyl)methyl]-(34274-05-0)

Safety Data

• Hazardous Substances Data: 34274-05-0(Hazardous Substances Data)

Upstream product

• 110-91-8 morpholine 
• 3840-30-0 5-(chloromethyl)-1,2,3-trimethoxybenzene 
• 21852-50-6 3,4,5-trimethoxybenzyl bromide 
• 6443-69-2 3,4,5-trimethoxytoluene 

Downstream Products

• 1529658-14-7 C₁₇H₂₇NO₈S 

Relevant articles and documents

Photochemical benzylic bromination in continuous flow using BrCCl3 and its application to telescoped p-methoxybenzyl protection

BrCCl3 represents a rarely used benzylic brominating reagent with complementary reactivity to other reagents. Its reactivity has been revisited in continuous flow, revealing compatibility with electron-rich aromatic substrates. This has brought about the development of a p-methoxybenzyl bromide generator for PMB protection, which was successfully demonstrated on a pharmaceutically relevant intermediate on 11 g scale, giving 91% yield and a PMB-Br space-time-yield of 1.27 kg L?1 h?1

N-2-hydroxyethyl N'-alkylpiperazines and benzylamines: Chemistry and pharmacology

The authors have prepared some benzylamine derivatives and established a structure-antidysrhythmic activity relationship. Most of the compounds exhibited significant activity. One also showed interesting anticalcium activity.