34295-27-7

Upstream product

• 5350-93-6 6-Chloro-pyridin-3-ylamine 
• 214360-73-3 4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)aniline 
• 171364-83-3 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nitrobenzene 
• 131941-28-1 2-(4-nitrophenyl)-5-nitropyridine 

Downstream Products

• 1597448-35-5 N-(6-(4-(furan-2-carboxamido)phenyl)pyridin-3-yl)furan-2-carboxamide 
• 1597448-39-9 3-methyl-N-(6-(4-(3-methylbutanamido)phenyl)pyridin-3-yl)butanamide 
• 1597448-38-8 N-(6-(4-(cyclohexanecarboxamido)phenyl)pyridin-3-yl)cyclohexanecarboxamide 
• 1597448-37-7 4-fluoro-N-(6-(4-(4-fluorobenzamido)phenyl)pyridin-3-yl)benzamide 
• 1597448-36-6 N-(6-(4-benzamidophenyl)pyridin-3-yl)benzamide 

Relevant academic research and scientific papers

Films of polyamides with phenylpyridine units in the backbone

New polyamides derived from 2-(4-aminophenyl)-5-aminopyridine, 4,4-diaminodiphenyl ether, and 4,4′-terephthaloyloxybis(3-methoxybenzoic) acid dichloride were prepared. These polyamides are of interest as macromolecular ligands. The deformation-strength, t

Nitrogenous aromatic heterocyclic nitro compound as well as preparation method and application thereof

The invention provides a nitrogen-containing aromatic heterocyclic nitro compound as well as a preparation method and application thereof. The nitrogenous aromatic heterocyclic nitro compound has a structure as shown in a formula (III), wherein X, Y and Z

Nitrogen-containing aromatic heterocyclic diamine and preparation method thereof

The invention provides nitrogen-containing aromatic heterocyclic diamine and a preparation method thereof. The nitrogen-containing aromatic heterocyclic diamine has a structure as shown in a formula (III); and in the formula (III), X, Y and Z are independently selected from C or N, at least two of X, Y and Z are C, and R0 is selected from NH2 or a group shown in the specifiation. Compared with the prior art, the preparation method provided by the invention has the advantages that the nitrogen-containing aromatic heterocyclic diamine with the specific structure is prepared by adopting a one-step method, the route is simple, the operation is simple and convenient, the reaction is efficient (the conversion rate is high and the selectivity is good), the post-treatment is convenient, the reaction substrate is suitable for broad spectrum, and the preparation method is suitable for industrial mass production.

Preparation method of diamido nitrogen-containing aromatic heterocycle compound

The invention relates to the technical field of synthesis of compounds, in particular to a preparation method of diamido nitrogen-containing aromatic heterocycle compound. The preparation method includes mixing a compound having the structure as shown as the formula (I) with inorganic acid, reacting to obtain water-soluble organism, performing reduction reaction with a reducing agent sulfide to effectively reduce nitro-organism into amino-compounds, performing neutral reaction with alkali liquor so as to obtain the diamido nitrogen-containing aromatic heterocycle compound having the structureas shown as the formula (II) and having high yield and purity. The preparation method is simple and environmental friendly, is low in cost, needs mild reaction conditions, and is suitable to be popularized and applied in scale. According to tests, the yield of the diamido nitrogen-containing aromatic heterocycle compound prepared by the method is not lower than 90%, and even can reach 96%, and itspurity can reach 99.9%.

A kind of benzene ring - aromatic ring series compound, its preparation method and medical use

The invention relates to a phenyl ring-aromatic ring cascaded micro-molecular organic compound which can be used as a protein-tyrosine-phosphatase subtype inhibitor and is shown in a general formula I as described in the specification. The compound can be used as a tool compound for research on the biological functions of a variety of subtypes of a protein-tyrosine-phosphatase family in cell signal transduction, so novel means is provided for prevention and treatment of cancers, metabolism and immunological diseases, cardiovascular diseases and nervous diseases. The invention also relates to a preparation method and medicinal application of the compound.