34298-84-5

Basic information

• Product Name: 2-(1H-INDOL-5-YL)ACETIC ACID
• Synonyms: 2-(1H-INDOL-5-YL)ACETIC ACID;AKOS VGU4014;RARECHEM AL MS 0097;1H-Indole-5-acetic acid
• CAS NO: 34298-84-5
• Molecular Formula: C₁₀H₉NO₂
• Molecular Weight: 175.18
• Mol File: 34298-84-5.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 415°C at 760 mmHg
• Flash Point: 204.8°C
• Appearance: /
• Density: 1.354g/cm³
• Vapor Pressure: 1.24E-07mmHg at 25°C
• Refractive Index: 1.693
• PKA: 4.41±0.30(Predicted)
• CAS DataBase Reference: 2-(1H-INDOL-5-YL)ACETIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(1H-INDOL-5-YL)ACETIC ACID(34298-84-5)
• EPA Substance Registry System: 2-(1H-INDOL-5-YL)ACETIC ACID(34298-84-5)

Safety Data

• Hazardous Substances Data: 34298-84-5(Hazardous Substances Data)

Usage

General Description

2-(1H-INDOL-5-YL)ACETIC ACID, also known as indole-3-acetic acid (IAA), is a naturally occurring plant hormone that belongs to the class of auxins. It plays a crucial role in various plant growth and developmental processes, such as cell elongation, apical dominance, and root initiation. IAA also influences tropic responses, such as phototropism and gravitropism, and is involved in the regulation of fruit development and ripening. In addition to its role in plants, IAA has been shown to have potential biomedical applications, including anti-cancer and anti-inflammatory properties, making it a molecule of interest in the pharmaceutical industry.

InChI:InChI=1/C10H9NO2/c12-10(13)6-7-1-2-9-8(5-7)3-4-11-9/h1-5,11H,6H2,(H,12,13)

Upstream product

• 33140-84-0 methyl 2-(1H-indol-5-yl)acetate 
• 209809-20-1 4-amino-3-bromophenylacetic acid methyl ester 
• 39552-81-3 methyl p-aminophenylacetate 
• 10075-50-0 5-bromo-1H-indole 

Downstream Products

• 1239447-50-7 N-(2-(3-benzoylphenyl)propyl)-2-(1H-indol-5-yl)acetamide 

Relevant articles and documents

HETEROCYCLIC COMPOUND, APPLICATION THEREOF, AND COMPOSITION CONTAINING SAME

A heterocyclic compound represented by formula XI, a pharmaceutically acceptable salt, a solvate, or a solvate of a pharmaceutically acceptable salt thereof, use thereof, and a composition containing the same. The compound is novel in structure and has good STAT5 inhibitory activity.

TRIAZOLE COMPOUNDS AS T-TYPE CALCIUM CHANNEL BLOCKERS

The invention relates to compounds of formula (I) wherein X, Y, R1, R2, (R4)n, and (R5)m are as defined in the description, and to pharmaceutically acceptable salts of such compounds. These compounds are useful as calcium T-channel blockers.

Aliphatic carboxamides

This invention provides a series of novel heterocyclic aliphatic carboxamides of formula I in which the group >Z--Y--XC=CH--NN--CH=CC=N--NN--N=C and the other radicals have the meanings defined in the following specification. The compounds of formula I are leukotriene antagonists. The invention also provides pharmaceutically acceptable salts of the formula I compounds; pharmaceutical compositions containing the formula I compound, or their salts, for use in the treatment of, for example, allergic or inflammatory diseases, or endotoxic or traumatic shock conditions; and processes for the manufacture of the formula I compounds, as well as intermediates for use in such manufacture.