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Pyrazinamine, also known as 6-(methylthio)-pyrazinamide (9CI), is a chemical compound with the molecular formula C6H7N3S. It is a derivative of pyrazinamide, a potent antituberculosis drug used in the treatment of tuberculosis. The compound features a pyrazine ring with an amino group at the 2-position and a methylthio group at the 6-position. Pyrazinamine is synthesized by reacting pyrazinamide with methyl iodide in the presence of a base, such as potassium carbonate. This chemical modification is aimed at enhancing the drug's activity or improving its pharmacokinetic properties. The compound is of interest in medicinal chemistry research, particularly in the development of new antituberculosis agents.

3430-08-8

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Basic information
1. Product Name: Pyrazinamine, 6-(methylthio)- (9CI)
2. Synonyms: Pyrazinamine, 6-(methylthio)- (9CI);6-(methylthio)pyrazin-2-amine;6-(methylthio)pyrazin-2-amine（WS202995）
3. CAS NO:3430-08-8
4. Molecular Formula: C5H7N3S
5. Molecular Weight: 141.19418
6. EINECS: N/A
7. Product Categories: VARIOUSAMINE
8. Mol File: 3430-08-8.mol
Chemical Properties
1. Melting Point: N/A
2. Boiling Point: N/A
3. Flash Point: N/A
4. Appearance: /
5. Density: N/A
6. Refractive Index: N/A
7. Storage Temp.: N/A
8. Solubility: N/A
9. CAS DataBase Reference: Pyrazinamine, 6-(methylthio)- (9CI)(CAS DataBase Reference)
10. NIST Chemistry Reference: Pyrazinamine, 6-(methylthio)- (9CI)(3430-08-8)
11. EPA Substance Registry System: Pyrazinamine, 6-(methylthio)- (9CI)(3430-08-8)
Safety Data
1. Hazard Codes: N/A
2. Statements: N/A
3. Safety Statements: N/A
4. WGK Germany:
5. RTECS:
6. HazardClass: N/A
7. PackingGroup: N/A
8. Hazardous Substances Data: 3430-08-8(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 3430-08-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,4,3 and 0 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 3430-08:
(6*3)+(5*4)+(4*3)+(3*0)+(2*0)+(1*8)=58
58 % 10 = 8
So 3430-08-8 is a valid CAS Registry Number.

3430-08-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name	6-methylsulfanylpyrazin-2-amine

1.2 Other means of identification

Product number	-
Other names	6-methylsulfanyl-pyrazin-2-ylamine

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:3430-08-8 SDS

3430-08-8Upstream product

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3430-08-8Relevant academic research and scientific papers

Pyrazinone thrombin inhibitors

-

, (2008/06/13)

Compounds of the invention are useful in inhibiting thrombin and associated thrombotic occlusions having the following structure: wherein

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