34304-58-0

Basic information

• Product Name: 5'-O-(4-monomethoxytrityl)-2'-O-(tetrahydropyran-2-yl)uridine
• Synonyms: 5'-O-(4-monomethoxytrityl)-2'-O-(tetrahydropyran-2-yl)uridine
• CAS NO: 34304-58-0
• Molecular Weight: 600.668
• Mol File: 34304-58-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5'-O-(4-monomethoxytrityl)-2'-O-(tetrahydropyran-2-yl)uridine(CAS DataBase Reference)
• NIST Chemistry Reference: 5'-O-(4-monomethoxytrityl)-2'-O-(tetrahydropyran-2-yl)uridine(34304-58-0)
• EPA Substance Registry System: 5'-O-(4-monomethoxytrityl)-2'-O-(tetrahydropyran-2-yl)uridine(34304-58-0)

Safety Data

• Hazardous Substances Data: 34304-58-0(Hazardous Substances Data)

Upstream product

• 14470-28-1 mono-4-methoxytrityl chloride 
• 50826-90-9 O^2'-tetrahydropyran-2-yl-uridine 

Downstream Products

• 162825-93-6 C₅₄H₅₈ClN₄O₁₇P 
• 51247-16-6 uridine 3'-(chlorophenyl) phosphate 
• 115142-05-7 uridine 3'-(2,5-dichlorophenyl) phosphate 
• 115142-06-8 uridine 3'-(p-nitrophenyl phosphate) 
• 115142-02-4 uridine 3'-(2-chlorophenyl) phosphate 
• 115142-01-3 uridine 3'-(4-chlorophenyl) phosphate 
• 2415-43-2 uridylyl-3',5'-uridine 

Relevant articles and documents

RNA modified uridines VII: Chemical synthesis and initial analysis of tRNA D-loop oligomers with tandem modified uridines

The first chemical synthesis of oligoribonucleotides with adjacent and significantly different modified uridines, the hydrophobic dihydrouridine, D, and the hydrophilic 3-[3-(S)-amino-3-carboxypropyl]-uridine, (acp)3U, is reported. The trimers Dp-acp3UpA, Up-acp3UpA, DpUpA and UpUpA, and the dimer Dp-acp3U were synthesized and initial structural analysis performed. The synthesis included a combination of protecting groups that is generally applicable to oligonucleotide syntheses in combination with various 2'OH protecting groups. The protecting groups did not cause racemization of the amino acid residue of (acp)3U during deprotection. The assignment of all 1H NMR resonances of modified nucleoside-containing oligoribonucleotides includes heteronuclear one and two dimensional NMR.