34314-63-1

Basic information

• Product Name: 3-OXAURACIL
• Synonyms: AURORA KA-3172;3-OXAURACIL;2H-1,3-OXAZINE-2,6-DIONE;2,3-dihydro-1,3-6h-oxazine-2,6-dione;2h-1,3-oxazine-2,6(3h)-dione;Brn 0112222;Nsc 163038;3H-1,3-oxazine-2,6-dione
• CAS NO: 34314-63-1
• Molecular Formula: C₄H₃NO₃
• Molecular Weight: 113.07
• Mol File: 34314-63-1.mol
• Article Data: 14

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.416g/cm³
• Refractive Index: 1.494
• Storage Temp.: -20°C
• CAS DataBase Reference: 3-OXAURACIL(CAS DataBase Reference)
• NIST Chemistry Reference: 3-OXAURACIL(34314-63-1)
• EPA Substance Registry System: 3-OXAURACIL(34314-63-1)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• Safety Statements: 36
• Hazardous Substances Data: 34314-63-1(Hazardous Substances Data)

Usage

Synthesis Reference(s)

The Journal of Organic Chemistry, 40, p. 743, 1975 DOI: 10.1021/jo00894a016

InChI:InChI=1/C4H3NO3/c6-3-1-2-5-4(7)8-3/h1-2H,(H,5,7)

Upstream product

• 557-24-4 maleamic acid 
• 151292-68-1 cis N-tert-butyloxycarbonyl dehydro β-alanine 
• 34314-62-0 3-trimethylsilanyl-3H-[1,3]oxazine-2,6-dione 
• 108-31-6 maleic anhydride 
• 4648-54-8 trimethylsilylazide 
• 541-59-3 maleiimide 

Downstream Products

• 58569-71-4 3-(tri-O-benzoyl-β-D-ribofuranosyl)-3H-[1,3]oxazine-2,6-dione 
• 75-07-0 acetaldehyde 
• 96355-24-7 5,9-Dihydro-3-(p-tolyl)-8H-1,2,4-triazino<5,6-b><1,4>diazepin-8-on 

Relevant articles and documents

The rid family member RutC of Escherichia coli is a 3-aminoacrylate deaminase

The Rid protein family (PF14588, IPR006175) is divided into nine subfamilies, of which only the RidA subfamily has been characterized biochemically. RutC, the founding member of one subfamily, is encoded in the pyrimidine utilization (rut) operon that encodes a pathway that allows Escherichia coli to use uracil as a sole nitrogen source. Results reported herein demonstrate that RutC has 3-aminoacrylate deaminase activity and facilitates one of the reactions previously presumed to occur spontaneously in vivo. RutC was active with several enamine-imine substrates, showing similarities and differences in substrate specificity with the canonical member of the Rid superfamily, Salmonella enterica RidA. Under standard laboratory conditions, a Rut pathway lacking RutC generates sufficient nitrogen from uracil for growth of E. coli. These results support a revised model of the Rut pathway and provide evidence that Rid proteins may modulate metabolic fitness, rather than catalyzing essential functions.

Carboxamide Compound and Use of the Same

A carboxamide compound represented by the formula (I): [wherein Q represents a nitrogen-containing 6-membered aromatic heterocyclic group optionally fused with a benzene ring, two or more ring constitutional atoms of the heterocyclic group are a nitrogen atom, and the heterocyclic group may be substituted with at least one group selected from the group consisting of a C1-C3 alkyl group etc.], and a plant disease controlling agent comprising this as an active ingredient.

METHODS OF TREATMENT AND PREVENTION OF NEURODEGENERATIVE DISEASES AND DISORDERS

The present invention provides compostions and methods useful for treating and preventing neurodegenerative disease and neurologically related disorders by inhibition of Lp-PLA2. The compositions and methods are useful for treating and preventing diseases