343248-67-9Relevant academic research and scientific papers
The synthesis of L-proline derived tetraazamacrocyclic ligands of C2 symmetry via intramolecular ester aminolysis
Achmatowicz, Michal,Jurczak, Janusz
, p. 111 - 119 (2007/10/03)
A convenient and efficient synthesis of enantiomerically pure 12-, 14-, and 16-membered tetraazamacrocyclic ligands, able to form complexes with transition metal cations, is discussed. Linear α,ω-aminoesters, prepared from L-proline, undergo intramolecular aminolysis to afford the corresponding macrocyclic amides in good yields.
