343266-68-2

Upstream product

• 610-72-0 2,5-dimethylbenzoic acid 
• 22328-43-4 2,5-dimethylbenzoyl chloride 
• 343266-89-7 N,N-diisopropyl-2,5-dimethylbenzamide 
• 74-88-4 methyl iodide 

Downstream Products

• 343266-72-8 (R)-(-)-2-(1-hydroxyethyl)ethyl-5-methylvalerophenone 
• 343266-74-0 (R)-2-(1-hydroxyethyl)ethyl-5-methylanisole 

Relevant academic research and scientific papers

Novel sparteine-mediated enantio-dichotomic formal synthesis of (R)-(-)- and (S)-(+)-curcuphenol

High and opposite enantiodiscriminations were observed between tertiary amides and secondary amides in the sparteine-mediated lateral metalation-allylation of 2-ethyl-m-toluamide derivatives (2a, 2e). The results described above have been applied for the formal synthesis of both enantiomers of curcuphenol. The brief mechanistic studies suggested that stereoinformation was introduced after the deprotonation step.