343309-52-4

Basic information

• Product Name: 2-(3-hydroxy-3,3-diphenylprop-1-yn-1-yl)phenol
• Synonyms: 2-(3-hydroxy-3,3-diphenylprop-1-yn-1-yl)phenol
• CAS NO: 343309-52-4
• Molecular Weight: 300.357
• Mol File: 343309-52-4.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2-(3-hydroxy-3,3-diphenylprop-1-yn-1-yl)phenol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-hydroxy-3,3-diphenylprop-1-yn-1-yl)phenol(343309-52-4)
• EPA Substance Registry System: 2-(3-hydroxy-3,3-diphenylprop-1-yn-1-yl)phenol(343309-52-4)

Safety Data

• Hazardous Substances Data: 343309-52-4(Hazardous Substances Data)

Upstream product

• 184368-89-6 1-iodo-2-(tert-butyldimethylsilyloxy)benzene 
• 119-61-9 benzophenone 
• 3923-52-2 1,1-diphenyl-2-propyn-1-ol 
• 32865-61-5 2-iodophenyl acetate 

Relevant articles and documents

BF3·Et2O-promoted cleavage of the Csp-Csp2 bond of 2-propynolphenols/anilines: Route to C2-alkenylated benzoxazoles and benzimidazoles

A novel BF3·Et2O-promoted tandem reaction of easily prepared 2-propynolphenols/anilines and trimethylsilyl azide is developed to give C2-alkenylated benzoxazoles and benzimidazoles in moderate to good yields. Most reactions could be accomplished in 30 min at room temperature. This tandem process involves a Csp-Csp2 bond cleavage and a C-N bond formation. Moreover, both tertiary and secondary propargylic alcohols with diverse functional groups were tolerated under the mild conditions.

Synthesis of Organophosphorus Compounds through Copper-Catalyzed Annulation Involving C-O and C-P Bond Formations

A novel copper(II) trifluoromethanesulfonate-catalyzed, high-efficiency, and atom-economical synthesis of valuable organophosphorus compounds via cascade annulation of propargylic alcohols with diphenylphosphine oxide is described. This protocol, which has a good functional-group compatibility and insensitivity to an ambient atmosphere, provides a simple and direct pathway to the products, organophosphorus compounds, in good yields under mild conditions. The method could be efficiently scaled up to gram scale, thus highlighting a potential application of this methodology.

Palladium-mediated intramolecular carbonylative annulation of o-alkynylphenols to synthesize benzo[b]furo[3,4-d]furan-1-ones.

[reaction in text] The carbonylative annulation of o-alkynylphenols mediated by PdCl(2)(PPh(3))(2) and dppp in the presence of CsOAc at 55 degrees C in acetonitrile under a balloon pressure of CO generates functionalized benzo[b]furo[3,4-d]furan-1-ones in