343313-30-4Relevant academic research and scientific papers
Preparation of branched ketones from esters via 1,2-disubstituted cyclopropanols. Synthesis of methylenomycin B
Shevchuk,Kulinkovich
, p. 1124 - 1126 (2007/10/03)
A cyclopentenoid antibiotic methylenomycin B was prepared by seven-stage synthesis from 1-ethyl-2-(2-hydroxypropyl)-1-cyclopropanol, a product of hydroxycyclopropanation of 4-penten-2-ol with ethyl propionate by treatment with isopropylmagnesium bromide in the presence of titanium(IV) isopropoxide.
